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| Name | Class |
|---|---|
| University of Guadalajara | OTHER |
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The protocol involves measurement of 25 hidroxy vitamin D, gene expression of cytochrome and vitamin D receptor , endoxifen, tamoxifen, exemestane, and other metobolites related to nutrition and endocrine metabolism.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Anastrozole | Breast cancer women with anastrozole treatment |
| |
| Tamoxifen | Breast cancer women with tamoxifen treatment |
| |
| Exemestane | Breast cancer women with exemestane treatment |
| |
| Basal | Breast cancer women luminal type without any endocrine treatment (at initial diagnosis) |
| |
| Recurrence | Breast cancer women luminal type with recurrence of disease during endocrine therapy |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Tamoxifen | Drug | Use of tamoxifen for breast cancer recurrence prevention |
|
| Measure | Description | Time Frame |
|---|---|---|
| Hidroxy Vitamin D Concentration | Plasma levels of Hidroxy Vitamin D | One time after minimum 3 months of tamoxifen, anastrozole or exemestane treatment (endocrine therapy) |
| Body Composition | Body composition (bioimpedance) | One time at enroll with at least 3 months of endocrine therapy |
| Measure | Description | Time Frame |
|---|---|---|
| Tamoxifen plasma levels | Tamoxifen plasma levels | One time. After minimum 3 months of tamoxifen treatment |
| Anastrozole | Anastrozole plasma levels |
| Measure | Description | Time Frame |
|---|---|---|
| Food consumption recall 24 hours (ASA 24) | Automated Self-Administered Recall System | At enroll |
Inclusion Criteria:
Exclusion Criteria:
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Mexican breast cancer woman
| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| JOSE ALFONSO CRUZ RAMOS, MD | Contact | 1523314886313 | josealfonsocr@gmail.com |
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Instituto Jalisciense de Cancerologia | Recruiting | Guadalajara | Jalisco | 45180 | Mexico |
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| Label | URL |
|---|---|
| Instituto Jalisciense de CancerologÃa | View source |
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Blood samples to obtain serum and DNA
| Exemestane | Drug | Use of exemestane for breast cancer recurrence prevention |
|
| Anastrozole | Drug | Use of anastrozole for breast cancer recurrence prevention |
|
| Basal | Diagnostic Test | Initial diagnosis of breast cacner by biopsy or mastectomy |
|
|
| Recurrence | Diagnostic Test | Breast cancer recurrence under endocrine therapy |
|
|
| One time. After minimum 3 months of anastrozole treatment |
| Exemestane | Exemestane plasma levels | One time. After minimum 3 months of exemestane treatment |
| Recurrence | Recurrence of breast cancer after endocrine therapy with tamoxifen or aromatase inhibitors | One time. In recurrence after at least 3 months with endocrine therapy |
| ID | Term |
|---|---|
| D001943 | Breast Neoplasms |
| D014808 | Vitamin D Deficiency |
| D009748 | Nutrition Disorders |
| D009765 | Obesity |
| ID | Term |
|---|---|
| D009371 | Neoplasms by Site |
| D009369 | Neoplasms |
| D001941 | Breast Diseases |
| D012871 | Skin Diseases |
| D017437 | Skin and Connective Tissue Diseases |
| D001361 | Avitaminosis |
| D003677 | Deficiency Diseases |
| D044342 | Malnutrition |
| D009750 | Nutritional and Metabolic Diseases |
| D050177 | Overweight |
| D044343 | Overnutrition |
| D001835 | Body Weight |
| D012816 | Signs and Symptoms |
| D013568 | Pathological Conditions, Signs and Symptoms |
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| ID | Term |
|---|---|
| D013629 | Tamoxifen |
| C056516 | exemestane |
| D000077384 | Anastrozole |
| ID | Term |
|---|---|
| D013267 | Stilbenes |
| D001597 | Benzylidene Compounds |
| D001555 | Benzene Derivatives |
| D006841 | Hydrocarbons, Aromatic |
| D006844 | Hydrocarbons, Cyclic |
| D006838 | Hydrocarbons |
| D009930 | Organic Chemicals |
| D009570 | Nitriles |
| D014230 | Triazoles |
| D001393 | Azoles |
| D006573 | Heterocyclic Compounds, 1-Ring |
| D006571 | Heterocyclic Compounds |
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