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Our goal is to determine if liposomal bupivacaine compared to standard bupivacaine results in increased pain control and decreased narcotic pain medication use when used in TAP blocks prior to laparoscopic hysterectomies for benign indications.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| TAP block with liposomal bupivacaine | Active Comparator | Active comparator |
|
| TAP block with 0.25% bupivacaine | Other | Standard comparator |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Transversus abdominis plane (TAP) block with liposomal bupivacaine | Procedure | Transversus abdominis plane (TAP) blocks are safe and effective procedures for the provision of postoperative pain management following abdominal procedures (3) and have been widely used across specialties with reduction in postoperative pain and narcotic use (4-7). |
| Measure | Description | Time Frame |
|---|---|---|
| Pain rating 1 hour post operation | Participant-reported pain rating on a numeric 0 - 10 scale, with rating of 0 representing no pain and rating 10 representing worst pain | 1 hour post operation |
| Pain rating 2 hours post operation | Participant-reported pain rating on a numeric 0 - 10 scale, with rating of 0 representing no pain and rating 10 representing worst pain | 2 hours post operation |
| Pain rating 4 hours post operation | Participant-reported pain rating on a numeric 0 - 10 scale, with rating of 0 representing no pain and rating 10 representing worst pain | 4 hours post operation |
| Pain rating 72 hours post operation | Participant-reported pain rating on a numeric 0 - 10 scale, with rating of 0 representing no pain and rating 10 representing worst pain | 72 hours post operation |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Melinda Abernethy, MD | Contact | (919) 260-9328 | melinda.abernethy@med.wmich.edu |
| Name | Affiliation | Role |
|---|---|---|
| Melinda Abernethy, MD | Western Michigan University Homer Stryker M.D. School of Medicine | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Bronson Methodist Hospital | Recruiting | Kalamazoo | Michigan | 49007 | United States |
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| ID | Term |
|---|---|
| D010149 | Pain, Postoperative |
| ID | Term |
|---|---|
| D011183 | Postoperative Complications |
| D010335 | Pathologic Processes |
| D013568 | Pathological Conditions, Signs and Symptoms |
| D010146 | Pain |
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| ID | Term |
|---|---|
| D003766 | Dental Occlusion |
| ID | Term |
|---|---|
| D003813 | Dentistry |
| D009063 | Dental Physiological Phenomena |
| D055688 | Digestive System and Oral Physiological Phenomena |
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|
| D009461 | Neurologic Manifestations |
| D012816 | Signs and Symptoms |