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| Name | Class |
|---|---|
| CareDx | INDUSTRY |
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The purpose of this study is to examine the feasibility and acceptability of a mobile app to improve self-management skills and medication adherence in kidney transplantation, to assess the clinical benefit of mobile app in combination with tailored coaching using text messaging to enhance patient activation, self-management and medication adherence and to determine whether immunological biomarkers such as cell-free DNA and donor specific antibodies are associated with self-management and medication adherence.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Interventional Group | Experimental | An app for tracking medications, receiving personal coaching and educational material |
|
| Control Group | Active Comparator | An app for tracking medications |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Smartphone App | Other | An app for monitoring medications, blood pressure, exercise, healthy eating |
|
| Measure | Description | Time Frame |
|---|---|---|
| Change in patient activation scores as measured by Patient Activation Measure | 0-100 scale that segments patients into one of four activation levels | baseline, 3 months, 6 months |
| Change in self-management as measured by Partners In Health survey | baseline, 3 months, 6 months |
| Measure | Description | Time Frame |
|---|---|---|
| Medication adherence as measured by self-tracking | up to 6 months | |
| Medication adherence as measured by blood levels | up to 6 months | |
| Presence of cell-free DNA |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Affiliation | Role |
|---|---|---|
| Eileen Chambers, MD | Duke University | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Duke University | Durham | North Carolina | 27710 | United States |
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| ID | Term |
|---|---|
| D055118 | Medication Adherence |
| ID | Term |
|---|---|
| D010349 | Patient Compliance |
| D010342 | Patient Acceptance of Health Care |
| D000074822 | Treatment Adherence and Compliance |
| D015438 | Health Behavior |
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| Tailored education | Behavioral | in-person coaching |
|
| up to 6 months |
| Presence of donor-specific antibodies | up to 6 months |
| Allograft function as measured by urine protein/creatinine ratio | up to 6 months |
| Allograft function as measured by serum creatinine | up to 6 months |
| D001519 | Behavior |