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Colchicine has antidiabetic effect and may be an option for type 2 diabetes management
Observational cohort prospective study with following of 150 newly diagnosed type 2 diabetes patients who were in 3 groups, had been monitored in a private clinic, each group 50 patients number, with 30 females and 20 males after written consent from all patients. The ages of all patients were between 35 and 55 years.
The aim of this study was to evaluate colchicine effect on A1C of newly diagnosed type2 diabetes compared to the metformin and control group on diet only.
The first group patients received colchicine 0.5twice daily for 6 months, the second group received metformin 1gm twice daily, the third group patients were on diet only. During the period of treatment, the investigators followed the patients if there were side effects of the drugs used. No side effects were monitored during the period of treatment except for gastric upset in some patients using metformin
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| group 1 on cochicine | The first group patients received colchicine 0.5 twice daily for 6 months |
| |
| group 2 on glucophage 1 gm twice daily | second group received glucophage 1gm twice daily for 6 months |
| |
| group 3 control | the third group patients were on diet only for 6 months |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Colchicine Tablets | Drug | colchicine tabletes for 6 months |
|
| Measure | Description | Time Frame |
|---|---|---|
| colchicine for treatment of type diabetes patients | colchicine tablets .5 mg twice daily for 6 months | 6 months |
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Inclusion Criteria:
Exclusion Criteria:
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Observational cohort prospective study with following of 150 newly diagnosed type 2 diabetes patients who were in 3 groups, had been monitored in a private clinic, each group 50 patients number, with 30 females and 20 males after written consent from all patients. The ages of all patients were between 35 and 55 years.
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Mahmoud Younis | Cairo | 11865 | Egypt |
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| ID | Term |
|---|---|
| D000074822 | Treatment Adherence and Compliance |
| D003924 | Diabetes Mellitus, Type 2 |
| ID | Term |
|---|---|
| D015438 | Health Behavior |
| D001519 | Behavior |
| D003920 | Diabetes Mellitus |
| D044882 | Glucose Metabolism Disorders |
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| ID | Term |
|---|---|
| D003078 | Colchicine |
| ID | Term |
|---|---|
| D000470 | Alkaloids |
| D006571 | Heterocyclic Compounds |
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| D008659 |
| Metabolic Diseases |
| D009750 | Nutritional and Metabolic Diseases |
| D004700 | Endocrine System Diseases |