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| ID | Type | Description | Link |
|---|---|---|---|
| U01CA229437-01 | U.S. NIH Grant/Contract | View source |
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| Name | Class |
|---|---|
| University of Michigan | OTHER |
| National Cancer Institute (NCI) | NIH |
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This study aims to identify states of vulnerability for lapse, identify states of receptivity for engaging in self-regulatory activities, and investigate approaches to capitalize on states of vulnerability and receptivity to deliver real-time self-regulation prompts among smokers.
Aim 1: Identify states of vulnerability for lapse: Self-reported and sensor-based measures will be used to identify empirically-based and theoretically-grounded features across multiple time scales that are most predictive of lapse. Operationalizing vulnerability in terms of the predicted level of risk for lapse, the investigators hypothesize that (H1) current vulnerability is represented by current and/or recent high negative emotions, low positive emotions, high craving, low self-efficacy, low self-regulatory capacity (SRC), and risky context (e.g., specific locations, such as a bar; cigarettes available; others smoking).
Aim 2: Identify states of receptivity for engaging in self-regulatory activities: Self-reported and sensor-based measures will be used to identify empirically-based and theoretically-grounded features across multiple time scales that are most predictive of engagement (i.e., usage of self-regulatory activities). Operationalizing receptivity in terms of the predicted likelihood of engagement, the investigators hypothesize that (H2) current receptivity is represented by high positive activating emotions (e.g., happy, grateful), low negative deactivating emotions (e.g., sad, boredom), low craving, high self-efficacy, high SRC, and low risk contexts (e.g., specific locations, such as home).
Aim 3: Investigate approaches to capitalize on states of vulnerability and receptivity to deliver real-time self-regulation prompts. Investigate whether, what type, and under what conditions (e.g., current state of vulnerability and/or receptivity) a prompt to engage the individual in self-regulatory activities increases engagement, hence reduces vulnerability.
The proposed research will help build a comprehensive conceptual, technical, and empirical foundation necessary to develop effective Just-in-Time-Adaptive-Interventions (JITAIs) based on dynamic models of vulnerability and receptivity. In the micro-randomized trial (MRT), Ecological momentary assessments (EMAs) are administered before and after JITAIs with items that are designed to measure different indices that may be related to participants' engagement of the JITAIs.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Brief cognitive/behavioral strategies | Experimental |
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| Effortful self-regulatory activities | Experimental |
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| No activities | No Intervention |
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Messages (participants experiencing negative affect & cigarettes are available) | Behavioral | Participants receive messages tailored for situations when they experiencing negative affect & cigarettes are available. |
| Measure | Description | Time Frame |
|---|---|---|
| Biochemically Verified Smoking Abstinence | Smoking abstinence will be completed via self-reported status from participants which are biochemically verified by either expired carbon monoxide via a breathalyzer or a cotinine sample as needed if a participant is unable to attend a visit in-person. | Post-quit date - 6-month follow-up |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Lindsey Potter, PhD | Contact | 801-213-6036 | lindsey.potter@hci.utah.edu | |
| Cho Lam, PhD | Contact | 8012136179 | cho.lam@hci.utah.edu |
| Name | Affiliation | Role |
|---|---|---|
| David Wetter, PhD | University of Utah | Principal Investigator |
| Inbal Nahum-Shani, PhD | University of Michigan | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| University of Utah | Recruiting | Salt Lake City | Utah | 84102 | United States |
Data will be shared with investigators working under an institution with a Federal Wide Assurance (FWA). Before sharing data, data will be stripped of all personal identifiers and all identifying codes. Data will be deemed either sensitive or low-risk, based on our characterization of the possibility of deductive disclosure. Request for sensitive data will be vetted through an assessment of both the requestor's credentials and potential risks. Note that our risk analysis will be based on a joint consideration of the total risk based on all data products requested.
The PIs and the research team will work to make the data available in a reasonable amount of time after its collection and following the acceptance for publication of the main findings. Rules for maintaining and distributing data of the University of Utah, the University of Michigan, and the NIH will be followed.
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| Type | Date | Date Unknown |
|---|---|---|
| Release | Nov 24, 2025 | |
| Reset | Dec 5, 2025 | |
| Release | Feb 25, 2026 |
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Micro-Randomized Trial (MRT) in the development of data-driven behavioral interventions.
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| Messages (participants not experiencing negative affect & cigarettes are available) | Behavioral | Participants receive messages tailored for situations when they cigarettes are available. |
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| Messages (participants experiencing negative affect & cigarettes are not available) | Behavioral | Participants receive messages tailored for situations when they experiencing negative affect. |
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| Messages (participants not experiencing negative affect & cigarettes are not available) | Behavioral | Generic messages for situations when participants are neither experiencing negative affect nor cigarettes are available. |
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| Moodsurf | Behavioral | Smart phone app that teaches participants a mindfulness-based technique in which participant "surf" the mood. |
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| Meditate | Behavioral | Smart phone app that teaches participants a mindfulness-based meditation designed for smoking cessation. |
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| Joy | Behavioral | Smart phone app that teaches participants to practice breathing exercise. |
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| Imagine | Behavioral | Smart phone app that teaches participants to use their imagination to explore and manage their thoughts and feelings. |
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| Notice | Behavioral | Smart phone app that teaches participants to accept their thoughts and feelings. |
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| Reset | Mar 18, 2026 |
| Release | May 15, 2026 |
| Reset | Jun 11, 2026 |
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| Release Date | Unrelease Date | Unrelease Date Unknown | Reset Date | MCP Release Number |
|---|---|---|---|---|
| Nov 24, 2025 | Dec 5, 2025 | |||
| Feb 25, 2026 | Mar 18, 2026 | |||
| May 15, 2026 | Jun 11, 2026 | |||
| Jul 1, 2026 |
| ID | Term |
|---|---|
| D000073869 | Tobacco Smoking |
| ID | Term |
|---|---|
| D012907 | Smoking |
| D001519 | Behavior |
| D064424 | Tobacco Use |
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| ID | Term |
|---|---|
| C578664 | cher protein, Drosophila |
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