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| Name | Class |
|---|---|
| Wuhan lung Hospital | UNKNOWN |
| Wuhan Central Hospital | OTHER |
| Wuhan University | OTHER |
| Ai You Foundation |
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The noval coronavirus disease 2019 (COVID-19) would cause physical and psychological dysfunctions in infected patients. We expect that an intelligence-based remote pulmonary rehabilitation scheme could improve patients' health status after hospital discharge. The intelligence-based remote pulmonary rehabilitation program is designed in a real-world and prospective manner, aiming to evaluate the efficacy of rehabilitation among 200 patients in the epicenter of China (Wuhan City) according to their varied adherence. An eight-week rehabilitation scheme, including two weeks for physicians and physiotherapists remotely guided training, and six weeks for patient self-management, will be addressed. The primary outcome of current study is six-minute walking distance and lung function, and secondly respiratory muscle strength, physical fitness assessment, symptoms and quality of life, etc. will also be assessed. Recruited patients will be followed up at week 2, 4, 8 after enrollment and at month 1, 3, 6, 12 after the rehabilitation training completed, respectively. The study has been approved by the ethics committee of China-Japan Friendship Hospital and three participating centers in Wuhan City.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Discharged COVID-19 patient cohort | All enrolled participants will be given 8 weeks (online 2 weeks + offline 6 weeks) pulmonary rehabilitation intervention, and will be followed up for at least one year, to assess their adherence and efficacy of the rehabilitation program. |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Remote pulmonary rehabilitation | Behavioral | The pulmonary rehabilitation intervention includes respiratory exercise, barehanded aerobic training, exercise prescription of elastic band impedance training, respiratory muscle strength training, etc. |
| Measure | Description | Time Frame |
|---|---|---|
| Six-minute walking distance (6MWD) | Walking distance within six minutes | One year |
| Pulmonary function | Forced expiratory volume in one second (FEV1), forced vital capacity (FVC), etc. | One year |
| Measure | Description | Time Frame |
|---|---|---|
| Respiratory muscle strength | Maximal inspiratory pressure, maximal expiratory pressure, etc. | One year |
| Physical fitness assessment | Two-minute walking test, short physical performance battery, grip strength of both upper limbs, knee extension strength of both lower limbs, etc. |
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Inclusion criteria:
Exclusion criteria:
One will be considered as withdrawal if consent is revoked, lost to follow-up, or unable to take the pulmonary rehabilitation scheme due to severe exacerbation, comorbidities, injury or trauma, etc.
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All discharged COVID-19 pneumonia patients who have signed the informed consent and met above eligibility criteria will be enrolled in this study.
| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Geyi Wen, Resident | Contact | +86 13263370980 | williamwgy@163.com | |
| Lulu Yang, Resident | Contact | +86 18810904716 | 1277403977@qq.com |
| Name | Affiliation | Role |
|---|---|---|
| Ting Yang, Prof. | China-Japan Friendship Hospital | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Wuhan Lung Hospital | Recruiting | Wuhan | Hubei | 100191 | China |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 34260823 | Derived | Lei J, Yang L, Wen G, Qumu S, Ren X, Yang T. Pulmonary telerehabilitation and efficacy among discharged COVID-19 patients: Rational and design of a prospective real-world study. Clin Respir J. 2021 Nov;15(11):1158-1167. doi: 10.1111/crj.13422. Epub 2021 Aug 6. |
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| UNKNOWN |
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| One year |
| Symptom | Modified British Medical Research Council (mMRC) dyspnea scale, etc. | One year |
| Psychological evaluation | Self-training depression scale (SDS) and self-rating anxiety scale (SAS) | One year |
| Quality of life | 36-item short-form health survey (SF-36), etc. | One year |
| Physical activity | International physical activity questionnaire (IPAQ) | One year |
| Proportion of returning to society | Proportions of returning to routine work and normal life | One year |
| Wuhan Central Hospital | Recruiting | Wuhan | Hubei | 430014 | China |
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| Zhongnan Hospital of Wuhan University | Recruiting | Wuhan | Hubei | 430071 | China |
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