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Patients with hemorrohoids grade II and III were included. Patients were randomized into 2 groups:
Bleeding, pain and stinging will be evaluated 14 days after beginning the treatment.
Patients with hemorrohoids grade II and III were included.
Patients were randomized into 2 groups:
Bleeding, pain and stinging will be evaluated 14 days after beginning the treatment. Quantification of pain will be performed following a visual analogic scale ranging from 0 (absence of symptoms) to 100 (unbearable symptoms).
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Vitamin E ovules | Experimental | Endoanal Vitamin E ovules will be prescriped during 14 days |
|
| Prednisolone ointment | Active Comparator | Endoanal Prednisolone ointment will be prescriped during 14 days |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Vitamin E ovules | Drug | Endoanal vitamin E ovules will be prescribed |
| |
| Measure | Description | Time Frame |
|---|---|---|
| % of patients with Bleeding | The patient refers rectal bleeding during defecation (patients“self-report) or active bleeding is observed at rectal examination. The variable will be measured as present (1) or absent(0) | 14 days after beginning the treatment |
| Measure | Description | Time Frame |
|---|---|---|
| Anal pain assessed by Visual Analogic Scale | The patients will be asked to quantify their perception of pain on a VAS, ranging from 0mm(absence of pain) to 100mm (unbearable pain) | 14 days after beginning the treatment |
| % of patients with Stinging |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Jaime Ruiz-Tovar | Contact | 630534808 | jruiztovar@gmail.com | |
| Carolina LLavero Garrido | Contact | 649593020 | carolinallavero@gmail.com |
| Name | Affiliation | Role |
|---|---|---|
| Jaime Ruiz Tovar Polo | Garcilaso Clinic | Principal Investigator |
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| ID | Term |
|---|---|
| D006471 | Gastrointestinal Hemorrhage |
| D010146 | Pain |
| D001733 | Bites and Stings |
| ID | Term |
|---|---|
| D005767 | Gastrointestinal Diseases |
| D004066 | Digestive System Diseases |
| D006470 | Hemorrhage |
| D010335 | Pathologic Processes |
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| ID | Term |
|---|---|
| C001122 | neomycin, prednisolone, surfen, trypsin-chymotrypsin drug combination |
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Symptoms will be assessed by a nurse blinded to the prescribed treatment
| Prednisolone ointment |
| Drug |
Endoanal Prednisolone ointment will be prescribed |
|
The patient refers stinging sensation (patients“self-report) . The variable will be measured as present (1) or absent(0)
| 14 days after beginning the treatment |
| D013568 |
| Pathological Conditions, Signs and Symptoms |
| D009461 | Neurologic Manifestations |
| D012816 | Signs and Symptoms |
| D011041 | Poisoning |
| D064419 | Chemically-Induced Disorders |
| D014947 | Wounds and Injuries |