Not provided
Not provided
| ID | Type | Description | Link |
|---|---|---|---|
| 2020-A00852-37 | Other Identifier | ID RCB |
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
The effects of severe acute respiratory syndrome SARS-Cov-2 (Covid-19) on the myocardium and their role in the clinical course of infected patients are still unknown. Epidemiological studies report biological myocardial involvement in 10 to 25% of cases. The objective of this study is to cardiac phenotype using comprehensive cardiac imaging tools of patients infected with Covid 19 in order to explore the functional impact of the infection on the myocardium.
A large population of Covid 19 infected patients of different ages and severity levels will be explored by transthoracic echocardiography with measurement of myocardial functional parameters such as ejection fraction, longitudinal strain and relaxation parameters and will be compared to an uninfected population paired for age and sex.
Patients with biological myocardial involvement will be followed to determine the evolution of their myocardial functional parameters during the course of the infection.
Not provided
Not provided
Not provided
Not provided
Not provided
| Label | Type | Description | Intervention Names |
|---|---|---|---|
| COVID + patients | Major patients hospitalized for respiratory criteria for SARS-Cov-2 infection confirmed by RT-PCR |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Global Longitudinal Strain | Diagnostic Test | Electrocardiogram with measure of the Global Longitudinal Strain to evaluate myocardiac dysfunction |
|
| Measure | Description | Time Frame |
|---|---|---|
| Left ventricular function | Left ventricular function evaluated by global longitudinal strain | Day 0 |
| Left ventricular function | Left ventricular function evaluated by global longitudinal strain | Day 3 |
| Left ventricular function | Left ventricular function evaluated by global longitudinal strain | Day 7 |
| Measure | Description | Time Frame |
|---|---|---|
| inflammatory biological parameters | Cytokine rate | Day 0 |
Not provided
Inclusion Criteria:
Exclusion Criteria:
Not provided
Not provided
Not provided
Major patients hospitalized for respiratory criteria for SARS-Cov-2 infection confirmed by RT-PCR
Not provided
| Name | Affiliation | Role |
|---|---|---|
| Vincent MINVILLE, PU-PH | University Hospital, Toulouse | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| UHToulouse | Toulouse | 31059 | France |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 34751159 | Derived | Lairez O, Blanchard V, Balardy L, Vardon-Bounes F, Cazalbou S, Ruiz S, Collot S, Houard V, Rolland Y, Conil JM, Minville V. COCARDE Study-Cardiac Imaging Phenotype in Patients With COVID-19: Protocol for a Prospective Observational Study. JMIR Res Protoc. 2022 Jan 6;11(1):e24931. doi: 10.2196/24931. |
Not provided
Not provided
Not provided
| ID | Term |
|---|---|
| D009202 | Cardiomyopathies |
| D000086382 | COVID-19 |
| ID | Term |
|---|---|
| D006331 | Heart Diseases |
| D002318 | Cardiovascular Diseases |
| D011024 | Pneumonia, Viral |
| D011014 | Pneumonia |
Not provided
Not provided
| ID | Term |
|---|---|
| D000094582 | Global Longitudinal Strain |
| ID | Term |
|---|---|
| D006439 | Hemodynamics |
| D002320 | Cardiovascular Physiological Phenomena |
| D002943 | Circulatory and Respiratory Physiological Phenomena |
Not provided
Not provided
Not provided
Not provided
Not provided
Inflammatory cytokines
| D012141 |
| Respiratory Tract Infections |
| D007239 | Infections |
| D014777 | Virus Diseases |
| D018352 | Coronavirus Infections |
| D003333 | Coronaviridae Infections |
| D030341 | Nidovirales Infections |
| D012327 | RNA Virus Infections |
| D008171 | Lung Diseases |
| D012140 | Respiratory Tract Diseases |