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While effects of specific exercise interventions on bone and CVD in postmenopausal women have been demonstrated and evaluated, the effects of randomized controlled exercise interventions, particularly in middle-aged premenopausal women are sparse. Therefore, it is imperative to examine the relation between behavioral interventions and bone and cardiovascular outcomes in premenopausal women as this understudied group is at high risk for the initial stages of bone loss and cardiovascular disease development.
Presently, it is not clear whether the intensity of Yoga interventions is high enough to induce positive effects on bone and cardiovascular health in a healthy population. For example, Hagins et al. (2007) reported that the metabolic costs of Hatha Yoga, averaged across the entire session, represent low levels of physical activity (walking). On the other hand, Ashtanga Yoga, or power Yoga, is performed at a higher intensity than Hatha Yoga and has been shown to elicit significantly higher heart rates than either Hatha or gentle Yoga (Cowen and Adams, 2007). Sun Salutations (SS) are an example of an Ashtanga Yoga sequence, where yoga postures are performed dynamically with combinations of forward and backward bending poses (Omkar et al., 2011). A previous 8-month yoga intervention found that regular long-term Ashtanga yoga had a small positive effect on bone formation in premenopausal women. Although Yoga has the potential to be an alternative physical activity to improve bone health and arterial stiffness, there is a lack of high-quality evidence for this type of intervention. Thus, the purpose of this study is to assess the feasibility of a 12-week home-based dynamic yoga intervention designed to improve bone metabolism and arterial stiffness in healthy premenopausal women.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Yoga group | Active Comparator | A certified yoga instructor led the supervised yoga session. An exercise physiologist taught how to record your Rating of Perceived Exertion to monitor their exercise intensity during the in-home yoga intervention. During the in-home yoga intervention, participants performed 30 to 50 minutes of yoga postures three to five times a week for 12 weeks. |
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| Control group | No Intervention | If participants were in a CON group, they did not receive the yoga intervention. Instead, they were encouraged to maintain a normal daily lifestyle monitored by the BPAQ at one-month intervals during the 12-week intervention. |
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Yoga group | Behavioral | During the in-home yoga intervention, participants performed 30 to 50 minutes of yoga postures three to five times a week for 12 weeks, including 5 minutes of warm-up exercise, 15 to 30 minutes of dynamic flow yoga postures, 10 minutes of weight barring standing postures, and 5 minutes of cool-down. These in-home sessions were a repeat of what participants learned during the first week of training session at UML. We progressively increased the intensity of the home practice sessions by adding the number of sun salutation (SS) over the 12 weeks. |
| Measure | Description | Time Frame |
|---|---|---|
| Change in Physical activity participation was assessed. | Participants were asked to fill out a physical activity questionnaire (BPAQ scores) Physical activity participation was estimated with the bone-specific physical activity questionnaire (BPAQ score). | BPAQ scores were collected at baseline, at 6 weeks, and after 12 weeks to see any differences throughout the intervention periods. |
| Change in Health history was assessed. | A health history questionnaire (HH) was utilized to examine any medical history that can affect bone and cardiovascular health. | HH questionnaires were collected at baseline, at 6 weeks, and after 12 weeks to see any changes throughout the intervention periods. |
| Change in menstrual history was assessed | A menstrual history questionnaire (MH) was used to determine if a participant was pregnant. | MH questionnaires were collected at baseline, at 6 weeks, and after 12 weeks to see any changes throughout the intervention periods. |
| Change in calcium intake was assessed | Daily calcium intake (mg/d) was estimated using a calcium intake questionnaire (CI). | CI questionnaires were collected at baseline, at 6 weeks, and after 12 weeks to see any changes throughout the intervention periods. |
| Change in Body Mass Index (BMI) was assessed | Height (cm) and weight (kg) were collected to calculate BMI (kg/m2). | Height and weight were collected at baseline and after 12 weeks. |
| Change in total fat mass was assessed | Total fat mass (g) was measured using Dual Energy-X-ray Absorptiometry. |
| Measure | Description | Time Frame |
|---|---|---|
| Change in Arterial stiffness was assessed | Arterial stiffness (m/s) was measured using Pulse Wave Velocity (PWV) to look at intervention effects. | Arterial stiffness was collected at baseline, at 6 weeks, and after 12 weeks |
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Inclusion Criteria:
Exclusion Criteria:
Females who have regular menstrual cycles
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| Name | Affiliation | Role |
|---|---|---|
| SoJung Kim, PhD | University of Massachusetts, Lowell | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| University of Massachusetts | Lowell | Massachusetts | 01854 | United States |
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| ID | Term |
|---|---|
| D010024 | Osteoporosis |
| ID | Term |
|---|---|
| D001851 | Bone Diseases, Metabolic |
| D001847 | Bone Diseases |
| D009140 | Musculoskeletal Diseases |
| D008659 | Metabolic Diseases |
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Participants were randomly assigned either a yoga intervention group or a control group.
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| Total fat mass was measured at baseline and after 12 weeks. |
| Change in bone free lean body mass was assessed | Bone free lean body mass (g) was measured using Dual Energy-X-ray Absorptiometry. | Bone free lean body mass was measured at baseline and after 12 weeks. |
| Change in %fat was assessed | %fat (%) was measured using Dual Energy-X-ray Absorptiometry. | %fat was measured at baseline and after 12 weeks. |
| Change in P1NP was assessed. | A blood draw (approximately 10 ml) was collected to investigate differences in bone formation marker (P1NP, ng/mL) | Blood draws were collected at baseline, at 6 weeks, and after 12 weeks. |
| Change in CTX was assessed | A blood draw (approximately 10 ml) was collected to investigate differences in bone resorption marker (CTX, ng/mL) | Blood draws were collected at baseline, at 6 weeks, and after 12 weeks. |
| D009750 |
| Nutritional and Metabolic Diseases |