Not provided
| ID | Type | Description | Link |
|---|---|---|---|
| 2019-004328-39 | EudraCT Number |
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Clinical trial to compare the effects of terlipressin and octreotide in the reduction of portal hypertension measured as hepatic venous pressure gradient (HVPG) in patients with liver cirrhosis
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Terlipressin IV bolus | Experimental | Terlipressin 1mg IV bolus |
|
| Terlipressin IV continuous infusion | Experimental | Terlipressin by IV continuous infusion at a rate of 2mg/day (max 4mg/day) during 2 hours |
|
| Octreotide IV bolus plus continuous infusion | Experimental | Octreotide 50mcg IV bolus plus continuous infusion at a rate of 50mcg/h during 2 hours |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Terlipressin | Drug | Terlipressin 1mg IV bolus |
| |
| Measure | Description | Time Frame |
|---|---|---|
| Change in HVPG | 30 minutes, 1 hour and 2 hours |
Not provided
Not provided
Inclusion Criteria:
Exclusion Criteria:
Not provided
Not provided
Not provided
Not provided
| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Juan Carlos Garcia-Pagan, MD | Contact | +34932275400 | 5790 | jcgarcia@clinic.cat |
Not provided
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Hospital Clinic | Barcelona | 08036 | Spain |
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
single blind
| Terlipressin |
| Drug |
Terlipressin by IV continuous infusion at a rate of 2mg/day (max 4mg/day) during 2 hours |
|
| Octreotide | Drug | Octreotide 50mcg IV bolus plus continuous infusion at a rate of 50mcg/h during 2 hours |
|
| ID | Term |
|---|---|
| D000077585 | Terlipressin |
| D015282 | Octreotide |
| ID | Term |
|---|---|
| D008236 | Lypressin |
| D014667 | Vasopressins |
| D010909 | Pituitary Hormones, Posterior |
| D010907 | Pituitary Hormones |
| D036361 | Peptide Hormones |
| D006728 | Hormones |
| D006730 | Hormones, Hormone Substitutes, and Hormone Antagonists |
| D009479 | Neuropeptides |
| D010455 | Peptides |
| D000602 | Amino Acids, Peptides, and Proteins |
| D009842 | Oligopeptides |
| D009419 | Nerve Tissue Proteins |
| D011506 | Proteins |
| D010456 | Peptides, Cyclic |
| D047028 | Macrocyclic Compounds |
| D011083 | Polycyclic Compounds |
Not provided
Not provided