The objective of this study is to quantify motor performance, this study will use an eye movement Fitts' task to examine the effects of cervical spine manipulation on participants with chronic neck pain and the subsequent changes to saccade movement time. This study will also include a head movement Fitts' task which has previously reported a reduction in head movement time in chronic neck pain participants after cervical spine manipulation.

This is an observational within-subjects design that involves a pre/post cervical spine manipulation intervention on participants (n=20) with chronic neck pain and asymptomatic controls (n=20). All participants will complete an eye movement and head movement Fitts' task before and after cervical spine manipulation to identify any changes in saccade and head movement time, saccade and head peak velocity, and time to peak saccade and head velocity.

The purpose of this study is to measure the effects of cervical spine manipulation on the motor performance of participants with and without chronic neck pain.

The objective of this pre/post design study is to apply spinal manipulation of the cervical spine to participants with chronic neck pain and participants who are asymptomatic for neck pain, and to measure the subsequent changes of movement time of the eyes during an eye movement Fitts' task using eye-tracker technology.

This study will also include a head movement Fitts' task, which has been previously shown to identify a reduction in head movement time in participants after receiving cervical spine manipulation. The head movement task, which has a biomechanical basis, will serve as a comparator to the eye movement task, which has a neurophysiologic basis. Changes in head and eye movement time are both measures of motor performance.

The hypothesis for the eye movement Fitts' task, is that the eye movement time will be increase with larger distances between targets and will not be affected by changes in target width. It is anticipated that the eye movement time will reduce in the neck pain group following spinal manipulation in comparison to the asymptomatic group. We hypothesize that during the head movement task, symptomatic participants will experience a decrease in head movement time as compared to the asymptomatic group after spinal manipulation. We further hypothesize that head movement time will be increase with larger target distances and smaller target widths.

Participants with neck pain:

Inclusion criteria

• Between the ages of 18 and 40
• Neck pain for at least 3 months
• Palpable spinal segmental fixations at C1-7
• Neck pain must be reproducible by neck movements and/or provocative
• Normal or corrected-to-normal vision

Exclusion criteria

• Contraindications to spinal manipulation
• Can't be calibrated during the eye movement Fitts task (excluded from eye movement test only)
• Progressive neurologic deficits
• Cervical spine trauma or surgery
• Infection, tumor, osteoporosis, inflammatory spondyloarthropathy, spinal fracture, and a history of vestibular/inner ear dysfunction
• Diagnosed with an autonomic disorder such as Horner's syndrome
• Any current ocular and/or retinal disease, Diabetes, a history of head trauma
• Currently using opioids, recreational drugs or have a history of substance abuse

Asymptomatic participants:

Inclusion criteria

• Between the ages of 18 and 40
• No neck pain for at least 3 months
• Palpable spinal segmental fixations at C1-7
• Normal or corrected-to-normal vision

Exclusion criteria

• Contraindications to spinal manipulation
• Can't be calibrated during the eye movement Fitts task (excluded from eye movement test only)
• Progressive neurologic deficits
• Cervical spine trauma or surgery
• Infection, tumor, osteoporosis, inflammatory spondyloarthropathy, spinal fracture, and a history of vestibular/inner ear dysfunction
• Diagnosed with an autonomic disorder such as Horner's syndrome
• Any current ocular and/or retinal disease, Diabetes, a history of head trauma
• Currently using opioids, recreational drugs or have a history of substance abuse

I will be sharing processed and analyzed data.

The results of this study will be prepared for dissemination first at relevant clinical and scientific conferences. Subsequently, this work will be submitted to a peer reviewed journal for consideration of publication. Datasets will be deposited in the University of Manitoba's Dataverse.

The data collected during this study may be shared in an anonymized or de-identified form with academic journals for publication purposes or other researchers according to international guidelines. The data may also be stored by the academic journal under an open access policy in which case it may be used by other researchers for further data analysis and research purposes. Before publishing/sharing any data, it will be reviewed with the Research Ethics Board or oversight committee to ensure full compliance with privacy legislation.

Uncertain as research has been placed on hold due to the COVID-19 pandemic.

Datasets will be deposited in the University of Manitoba's Dataverse. Dataverse is an open source web application to share, preserve, cite, explore, and analyze research data.