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| ID | Type | Description | Link |
|---|---|---|---|
| NCI-2021-10775 | Other Identifier | CTRP |
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Pediatric Oncologic Recovery Trial After Surgery (PORTS) trial is an investigator-initiated, multicenter, multidisciplinary prospective case-control study of the implementation of an Enhanced Recovery After Surgery (ERAS) protocol at five tertiary-care pediatric hospitals in pediatric patients undergoing abdominal or retroperitoneal surgical resections for cancer. A pilot phase will determine characteristics of a successful protocol implementation and an exploratory phase plans to examine adherence, objective patient outcomes, and patient-reported outcomes. After completing primary enrollment, this collaborative will continue to enroll patients in the shared data registry and continue to refine the underlying ERAS protocol developed for this project.
Two arms:
Historical patients ERAS patients
Number of patients: 288
Primary outcome
· Number of 90-day complications by Clavien-Dindo classification
Secondary outcome(s):
Adherence to ERAS protocol items with # of items achieved (out of 20)
Length of stay
Re-admissions within 90 days
Re-operations within 90 days
Number of visits to the emergency room within 90 day period
Minimum, mean, maximum daily pain score during first 7 days after surgery
Mean daily IV morphine equivalents (mg/kg) usage during first 7 days after surgery
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Historical | Retrospective Review |
| |
| ERAS Patients | Prospective Review |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Observational | Other | Enhanced Recovery After Surgery protocol at five tertiary-care pediatric hospitals in pediatric patients undergoing abdominal or retroperitoneal surgical resections for cancer. |
| Measure | Description | Time Frame |
|---|---|---|
| Number of 90-day complications by Clavien-Dindo classification | 90 Days |
| Measure | Description | Time Frame |
|---|---|---|
| Number of Adherence issues to ERAS protocol items with # of items achieved (out of 20) | 90 Days | |
| Length of stay | 90 Days | |
| Number of Re-admissions within 90 days |
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Inclusion Criteria:
Exclusion Criteria:
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Pediatric patients undergoing urological surgery
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| Name | Affiliation | Role |
|---|---|---|
| Kyle Rove, MD | Children's Hospital Colorado | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Children's Hospital Colorado | Aurora | Colorado | 80045 | United States | ||
| Cincinnati Children's Hospital Medical Center |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 38840973 | Derived | Mansfield SA, Kotagal M, Hartman S, Murphy AJ, Davidoff AM, Anghelescu DL, Mecoli M, Cost N, Hogan B, Rove KO. Development of an enhanced recovery after surgery program for pediatric solid tumors. Front Surg. 2024 May 22;11:1393857. doi: 10.3389/fsurg.2024.1393857. eCollection 2024. |
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| ID | Term |
|---|---|
| D010386 | Pelvic Neoplasms |
| ID | Term |
|---|---|
| D009371 | Neoplasms by Site |
| D009369 | Neoplasms |
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| ID | Term |
|---|---|
| D057832 | Watchful Waiting |
| ID | Term |
|---|---|
| D017063 | Outcome Assessment, Health Care |
| D010043 | Outcome and Process Assessment, Health Care |
| D011787 | Quality of Health Care |
| D006298 | Health Services Administration |
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|
| 90 Days |
| Number of Re-operations within 90 days | 90 Days |
| Number of visits to the emergency room within 90 day period | 90 Days |
| VAS daily pain score during first 7 days after surgery | 90 Days |
| Mean daily IV morphine equivalents (mg/kg) usage during first 7 days after surgery | 90 Days |
| Recurrence free survival (months) | 90 Days |
| Overall survival (months) | 90 Days |
| Cincinnati |
| Ohio |
| 45229 |
| United States |
| St Jude Children's Research Hospital | Memphis | Tennessee | 38105 | United States |