Hyperbaric Oxygen Therapy (HBOT) as a Treatment for COVID-19 (COVID-19) Infection

Hyperbaric Oxygen Therapy (HBOT) as a Treatment for COVID-19 (COVID-19) Infection

Patients who meet inclusion criteria will be randomized into treatment vs control group. Treatment groups will undergo Hyperbaric Oxygen Therapy (HBOT) and compared to the control group.

After enrollment, patients will be randomized into treatment vs control group. Both populations will receive the same inpatient medical treatment. All patients in the treatment group will undergo hyperbaric oxygen therapy under the same treatment protocol. After completion of the treatment protocol, specific study endpoints will be compared between the treatment and control groups.

Inclusion Criteria:

• Adult inpatients >18 years old
• Positive PCR COVID-19 testing
• CT evidence of interstitial opacity
• Oxygen saturation <90% on room air
• pO2 = 55-70.

Exclusion Criteria:

• Increased oxygen requirements
• Hemodynamic instability (MAP<65)
• Bradycardia (HR<50)
• History of seizure disorder
• Pneumothorax
• GFR<30
• Hemodialysis
• Refractory anxiety/claustrophobia
• Current pregnancy
• Uncorrectable hypoglycemia