Intra-operative PET-CT: a Novel Approach to Determine Excision Margins in Lumpectomy Breast Cancer.

Intra-operative PET-CT: a Novel Approach to Determine Excision Margins in Lumpectomy Breast Cancer.

Examination of the feasibility of intra-operative pet CT to detect surgical margins in breast conservative surgery to prevent re-excision.

Inclusion Criteria:

• • female and 18 years of age or older

  • diagnosed with an early-stage (T1 or T2, and N0 or N1; according to the TNM-classification) invasive breast cancer
  • eligible for breast conserving surgery

Exclusion Criteria:

• • Pregnancy or lactation

  • Diabetes
  • Multifocal tumor disease
  • Diagnosis of inflammatory breast cancer
  • Appointment at the nuclear medicine department for 18F-FDG administration would result in a unacceptable delay of surgery
  • Subject has had exposure to ionizing radiation of more than 1 mSv in other research studies within the last 12 months
  • Subject has recently (<60 days) or is simultaneously participating in another clinical trial.