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Evaluate HACOR socre utility and efficacy in predicting NIV and/or CPAP failure in patients with COVID-19 associated respiratory failure.
Propose adaptations to HACOR score based on the "state of art" of COVID-19
Evaluate HACOR socre utility and efficacy in predicting NIV and/or CPAP failure in patients with COVID-19 associated respiratory failure.
Propose adaptations to HACOR score based on the "state of art" of COVID-19
- this adaptations may include radiologic aggravation and monitoring of CRF, ferritin, LDH, d-dimers, NT-proBNP, troponin I, GOT, GPT, blood count
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| NIV | Patients on Bilevel NIV |
| |
| CPAP | Patients on CPAP |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Monitoring for aggravation | Other | Monitor patients on CPAP or NIV and analyzing possible variables that may predict failure, namely:
|
| Measure | Description | Time Frame |
|---|---|---|
| HACOR score efficacy | Analyze if HACOR score is effective in predicting nonivasive ventilation failure in COVID-19 associated respiratory failure | 1 hour after initation of CPAP or NIV |
| HACOR score addaptation | Analyze the role of possible variables to be added to HACOR score in order to improve efficay in COVID-19 patients | 1 - 2 weeks |
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Inclusion Criteria:
Exclusion Criteria:
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Patients with acute respiratory failure due to COVID-19 who have initiated NIV or CPAP based on assistant clinician decision
| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Miguel Guia | Contact | 00351915774975 | miguelguia7@gmail.com | |
| Antonio Esquinas | Contact | 0034609321966 | antmesquinas@gmail.com |
| Name | Affiliation | Role |
|---|---|---|
| Miguel Guia | Hospital General Universitario Morales Meseguer | Principal Investigator |
| Antonio Esquinas | Hospital General Universitario Morales Meseguer | Study Director |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Hospital General Universitario Morales Meseguer | Recruiting | Murcia | Spain |
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| ID | Term |
|---|---|
| D012131 | Respiratory Insufficiency |
| D000086382 | COVID-19 |
| ID | Term |
|---|---|
| D012120 | Respiration Disorders |
| D012140 | Respiratory Tract Diseases |
| D011024 | Pneumonia, Viral |
| D011014 | Pneumonia |
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Blood sample for biochemistry and blood count
|
| Evaluate HACOR score effectivity in this patients | Other | Apply the HACOR score after starting NIV and CPAP and later verify if it was effective in predicting NIV/CPAP failure |
|
| D012141 |
| Respiratory Tract Infections |
| D007239 | Infections |
| D014777 | Virus Diseases |
| D018352 | Coronavirus Infections |
| D003333 | Coronaviridae Infections |
| D030341 | Nidovirales Infections |
| D012327 | RNA Virus Infections |
| D008171 | Lung Diseases |