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| ID | Type | Description | Link |
|---|---|---|---|
| 2020-A00906-33 | Other Identifier | ID-RCB number,ANSM |
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There is no predictive tool for patients admitted to the emergency department with a suspicion of Covid-19 that will worsen secondarily and require a heavy lifting.
In a context of saturation of the healthcare system by the pandemic at Covid-19,it is essential to identify specific, accessible prognostic markers via minimally invasive sampling with low risk of infection for personnel caregiver, for optimal allocation of resuscitation resources.
This study proposes to evaluate the biological markers of routine care known to be associated with resuscitation admission in relation to hospitalization on conventional service for the prediction of worsening of patients admitted to the emergencies for Covid-19.
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| Measure | Description | Time Frame |
|---|---|---|
| Rate of secondary aggravation | Secondary aggravation is defined as :
| an average at 30 days (- 2 days +3 days) of admission to the emergency department |
| Measure | Description | Time Frame |
|---|---|---|
| Change of standart biological parameters | the number of leukocytes, lymphocytes, neutrophil polynuclear cells, CRP, fibrinogen, and the D-dimers. | Between baseline and an average at 30 days (- 2 days +3 days) of admission to the emergency department |
| Change of Von willebrand factor (vWF) changes over time |
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Inclusion Criteria:
Exclusion Criteria:
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Adult population presenting to the emergency department during this pandemic period with symptoms suggestive of Covid-19 infection with no other probable diagnosis.
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| Name | Affiliation | Role |
|---|---|---|
| Delphine Garrigue, MD | University Hospital, Lille | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Hôpital Roger Salengro, CHU Lille | Lille | 59037 | France |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 41093046 | Derived | Ledoult E, Guerrier T, Dubucquoi S, Figeac M, Villenet C, Daunou B, Behal H, Pokeerbux MR, Machet T, Koether V, Collet A, Launay D; Lille Covid Research network (LICORNE). Dual role of plasmablasts as immune regulators or amplifiers in COVID-19. Clin Immunol. 2025 Dec;281:110609. doi: 10.1016/j.clim.2025.110609. Epub 2025 Oct 13. |
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| ID | Term |
|---|---|
| D014777 | Virus Diseases |
| D018352 | Coronavirus Infections |
| D000086382 | COVID-19 |
| ID | Term |
|---|---|
| D007239 | Infections |
| D003333 | Coronaviridae Infections |
| D030341 | Nidovirales Infections |
| D012327 | RNA Virus Infections |
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| Between baseline and an average at 30 days (- 2 days +3 days) of admission to the emergency department |
| Change of the Factor VIII (FVIII) | Between baseline and an average at 30 days (- 2 days +3 days) of admission to the emergency department |
| Prevalence of positivity of COVID-19 virus measured by PCR or serology | an average at 30 days (- 2 days +3 days) of admission to the emergency department |
| D011024 |
| Pneumonia, Viral |
| D011014 | Pneumonia |
| D012141 | Respiratory Tract Infections |
| D008171 | Lung Diseases |
| D012140 | Respiratory Tract Diseases |