Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Covid-SER is a prospective multi-center study for the evaluation of diagnostic performance of available serological tests
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Serological tests will be applied on patients blood sampling | Experimental | Serological tests will be applied on patients blood sampling |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Serological tests will be applied on patients blood sampling | Diagnostic Test | Application of tests on patients' serum |
|
| Measure | Description | Time Frame |
|---|---|---|
| The positivity (Yes/No) of the serological test. | The sensitivity and specificity of serological tests (positive or negative) compared to molecular detection of the virus by PCR | Day 0 |
| The positivity (Yes/No) of the serological test. | The sensitivity and specificity of serological tests (positive or negative) compared to molecular detection of the virus by PCR | Day 3 |
| The positivity (Yes/No) of the serological test. | The sensitivity and specificity of serological tests (positive or negative) compared to molecular detection of the virus by PCR | Day 7 |
| The positivity (Yes/No) of the serological test. | The sensitivity and specificity of serological tests (positive or negative) compared to molecular detection of the virus by PCR | Day 14 |
| The positivity (Yes/No) of the serological test. | The sensitivity and specificity of serological tests (positive or negative) compared to molecular detection of the virus by PCR | Day 21 |
| The positivity (Yes/No) of the serological test. | The sensitivity and specificity of serological tests (positive or negative) compared to molecular detection of the virus by PCR | Day 28 |
| The positivity (Yes/No) of the serological test. | The sensitivity and specificity of serological tests (positive or negative) compared to molecular detection of the virus by PCR |
Not provided
Not provided
Inclusion Criteria:
Exclusion Criteria:
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Hôpital Lyon Sud,Sainte Eugénie bat 4M,5, Chemin du Grand Revoyet | Pierre-Bénite | 69495 | France |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 33450388 | Result | Bal A, Trabaud MA, Fassier JB, Rabilloud M, Saker K, Langlois-Jacques C, Guibert N, Paul A, Alfaiate D, Massardier-Pilonchery A, Pitiot V, Morfin-Sherpa F, Lina B, Pozzetto B, Trouillet-Assant S; COVID SER Study Group. Six-month antibody response to SARS-CoV-2 in healthcare workers assessed by virus neutralization and commercial assays. Clin Microbiol Infect. 2021 Jun;27(6):933-935. doi: 10.1016/j.cmi.2021.01.003. Epub 2021 Jan 13. No abstract available. | |
| 34294751 |
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
| Day 35 |
| The positivity (Yes/No) of the serological test. | The sensitivity and specificity of serological tests (positive or negative) compared to molecular detection of the virus by PCR | Day 42 |
| Result |
| Bal A, Brengel-Pesce K, Gaymard A, Queromes G, Guibert N, Frobert E, Bouscambert M, Trabaud MA, Allantaz-Frager F, Oriol G, Cheynet V, d'Aubarede C, Massardier-Pilonchery A, Buisson M, Lupo J, Pozzetto B, Poignard P, Lina B, Fassier JB, Morfin F, Trouillet-Assant S; COVID-SER Study group. Clinical and laboratory characteristics of symptomatic healthcare workers with suspected COVID-19: a prospective cohort study. Sci Rep. 2021 Jul 22;11(1):14977. doi: 10.1038/s41598-021-93828-y. |
| 34673755 | Result | Pozzetto B, Legros V, Djebali S, Barateau V, Guibert N, Villard M, Peyrot L, Allatif O, Fassier JB, Massardier-Pilonchery A, Brengel-Pesce K, Yaugel-Novoa M, Denolly S, Boson B, Bourlet T, Bal A, Valette M, Andrieu T, Lina B; Covid-Ser study group; Cosset FL, Paul S, Defrance T, Marvel J, Walzer T, Trouillet-Assant S. Immunogenicity and efficacy of heterologous ChAdOx1-BNT162b2 vaccination. Nature. 2021 Dec;600(7890):701-706. doi: 10.1038/s41586-021-04120-y. Epub 2021 Oct 21. |
| 33234651 | Result | Trouillet-Assant S, Albert Vega C, Bal A, Nazare JA, Fascia P, Paul A, Massardier-Pilonchery A, D Aubarede C, Guibert N, Pitiot V, Lahousse M, Boibieux A, Makhloufi D, Simon C, Rabilloud M, Trabaud MA, Gueyffier F, Fassier JB; COVID-SER study group. Assessment of serological techniques for screening patients for COVID-19 (COVID-SER): a prospective, multicentric study. BMJ Open. 2020 Nov 24;10(11):e041268. doi: 10.1136/bmjopen-2020-041268. |
| 36173972 | Result | de Boer J, Saade U, Granjon E, Trouillet-Assant S, Saade C, Pottel H, Zrein M; Covid ser study group. A novel assessment method for COVID-19 humoral immunity duration using serial measurements in naturally infected and vaccinated subjects. PLoS One. 2022 Sep 29;17(9):e0274553. doi: 10.1371/journal.pone.0274553. eCollection 2022. |
| 33399823 | Result | Bal A, Pozzetto B, Trabaud MA, Escuret V, Rabilloud M, Langlois-Jacques C, Paul A, Guibert N, D'Aubarede-Frieh C, Massardier-Pilonchery A, Fabien N, Goncalves D, Boibieux A, Morfin-Sherpa F, Pitiot V, Gueyffier F, Lina B, Fassier JB, Trouillet-Assant S; COVID SER Study Group. Evaluation of High-Throughput SARS-CoV-2 Serological Assays in a Longitudinal Cohort of Patients with Mild COVID-19: Clinical Sensitivity, Specificity, and Association with Virus Neutralization Test. Clin Chem. 2021 Apr 29;67(5):742-752. doi: 10.1093/clinchem/hvaa336. |