Gastric carcinoma is the second most common cause of cancer-related deaths and its main treatment modality if potentially curable is surgery but the optimal surgical resection is controversial. The aim of the current study was to assess the outcomes of curative D2 compared to D1 gastrectomy of operable gastric carcinoma regarding postoperative morbidity and mortality, disease recurrence and survival rates.

80 consecutive patients with potentially operable gastric carcinoma were randomized via concealed envelopes into 2 groups (each included 40 patients), group I managed by radical gastrectomy with D1 lymphadenectomy while group II managed by radical gastrectomy with D2 lymphadenectomy . Both groups were compared regarding postoperative mortality, morbidities, tumor recurrence and 2 years survival rates.

Inclusion Criteria:

• Histologically confirmed gastric carcinoma
• Potentially operable gastric carcinoma without evidence of distant metastasis

Exclusion Criteria:

• Complicated gastric cancer (obstructed or perforated)
• Locally irresectable tumor
• Previous or coexisting cancer
• Prior gastric surgery or neoadjuvant chemotherapy
• Contraindication for major surgery

Randomization by opaque sealed envelopes