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assess the safety and effectiveness of using low-flow extracorporeal membrane oxygenation(CO2 removal) driving by CVVH machine in the severe NCP patients
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| NCP patient with severe ARDS and/or high ventilator supported | Experimental | The NCP patient with severe ARDS and/or high ventilator supported condition was eligibilitable for enrollment |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Low flow ECMO driving by CVVH machine | Device | With aim to clear CO2 and improve oxygenation, a low flow ECMO treatment(using oxgyenator membrane of kid type ) driving by CVVH machine will be performed in the NCP with severe ARDS |
| Measure | Description | Time Frame |
|---|---|---|
| PaCO2 | PaCO2 from blood gas analysis | Day 1 |
| Driving Pressure | Driving Pressure monitor by ventilator | Day 1 |
| Tidal volume | Tidal volume monitor by ventilator | Day 1 |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Yun Long, MD | Contact | +8610169152300 | ly_icu@aliyun.com | |
| Yun Long | Contact | +8610169152300 | ly_icu@aliyun.com |
| Name | Affiliation | Role |
|---|---|---|
| Yun Long | Peking Union Medical College Hospit | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Yun Long | Recruiting | Beijing | Beijing Municipality | 100730 | China |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 34307397 | Derived | Ding X, Chen H, Zhao H, Zhang H, He H, Cheng W, Wang C, Jiang W, Ma J, Qin Y, Liu Z, Wang J, Yan X, Li T, Zhou X, Long Y, Zhang S. ECCO2R in 12 COVID-19 ARDS Patients With Extremely Low Compliance and Refractory Hypercapnia. Front Med (Lausanne). 2021 Jul 8;8:654658. doi: 10.3389/fmed.2021.654658. eCollection 2021. |
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| ID | Term |
|---|---|
| D000086382 | COVID-19 |
| ID | Term |
|---|---|
| D011024 | Pneumonia, Viral |
| D011014 | Pneumonia |
| D012141 | Respiratory Tract Infections |
| D007239 | Infections |
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| D014777 |
| Virus Diseases |
| D018352 | Coronavirus Infections |
| D003333 | Coronaviridae Infections |
| D030341 | Nidovirales Infections |
| D012327 | RNA Virus Infections |
| D008171 | Lung Diseases |
| D012140 | Respiratory Tract Diseases |