Gut Microbiota Metagenomics for Chronic Liver Disease

Research Based on Gut Microbiota Metagenomics for Prevention of Chronic Liver Disease

Gut microbiota modulation has effect on chronic liver disease

Chronic liver disease has been known as a disease of the liver which lasts over a period of 6-month. It consists of inflammation, hepatitis, cirrhosis, hepatocellular carcinoma.

Gut microbiota plays an important roles in the chronic liver disease. It can suppress the progression of the liver disease by moulation gut microbiota.

The investigators are still evaluating the effect of gut microbiota on the liver disease.

Inclusion Criteria:

• Age 19+
• Normal : AST or ALT level < 50IU/L, BMI < 25
• Liver disease : AST or ATL level ≥ 50IU/L, BMI ≥ 25
• Patients hospitalized with chronic liver disease (viral hepatitis, alcoholic liver disease, non-alcoholic liver disease, cirrhosis, liver cancer)

Exclusion Criteria:

• Normal : AST or ATL level ≥ 50IU/L, BMI ≥ 25
• Liver disease : AST or ALT level < 50IU/L, BMI < 25
• If the patient refuses