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| Name | Class |
|---|---|
| Pr. Jean-Benoît THAMBO, Bordeaux (président) | UNKNOWN |
| Dr. Céline GRUNENWALD GRONIER, Strasbourg | UNKNOWN |
| Dr. Sébastien HASCOET, Le Plessis-Robinson | UNKNOWN |
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The ongoing Coronavirus (Covid-19) pandemic has recently generated the first epidemiological data on populations at risk. Currently, the risk factors, recognized for severe forms of Covid-19 infection, are elderly patients (> 70 years), obese patients, patients with chronic renal or respiratory diseases, cardiovascular history (stroke or coronary artery disease), high blood pressure, diabetes, and cancer.
The population of congenital heart disease (CHD) might also be at risk, however, no data is available in this group of patients.
CHD is the leading cause of birth defects, and as a result of recent medical advances, currently the number of adults with CHD exceeds the number of children, with an increasing prevalence of complex CHD. Approximately 200,000 children and 250,000 adults are living with a CHD in France today.
The French Society of Cardiology, coordinator of this study, issued recommendations on March 14, 2020 for the French CHD population on the basis of expert opinions based essentially on the data published in the general population. Nevertheless, there is a need to provide scientific data on the impact of Covid-19 in the pediatric and adult CHD population.
This study aims to assess the morbidity, the mortality and the risk factors associated with Covid-19 in patients with CHD in France
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| Measure | Description | Time Frame |
|---|---|---|
| Prevalence of Covid-19 infection in the overall CHD population | Prevalence of Covid-19 infection in the overall CHD population | through study completion, an average of 2 weeks |
| Measure | Description | Time Frame |
|---|---|---|
| Prevalence of Covid-19 infection per CHD sub-group | Prevalence of Covid-19 infection per CHD sub-group | through study completion, an average of 2 weeks |
| Cardiovascular complications | Cardiovascular complications |
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Inclusion criteria:
Exclusion criteria:
- Patient with genetic heart disease (cardiomyopathy, hereditary rhythmic disease).
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Peadiatric and adult patient with congenital heart disease and COVID-19
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| Name | Affiliation | Role |
|---|---|---|
| Pascal AMEDRO, MD-PhD | UH MONTPELLIER | Study Director |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Uh Montpellier | Montpellier | 34295 | France |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 17210844 | Background | Marelli AJ, Mackie AS, Ionescu-Ittu R, Rahme E, Pilote L. Congenital heart disease in the general population: changing prevalence and age distribution. Circulation. 2007 Jan 16;115(2):163-72. doi: 10.1161/CIRCULATIONAHA.106.627224. Epub 2007 Jan 8. | |
| 32091533 | Background | Wu Z, McGoogan JM. Characteristics of and Important Lessons From the Coronavirus Disease 2019 (COVID-19) Outbreak in China: Summary of a Report of 72 314 Cases From the Chinese Center for Disease Control and Prevention. JAMA. 2020 Apr 7;323(13):1239-1242. doi: 10.1001/jama.2020.2648. No abstract available. |
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| ID | Term |
|---|---|
| D006330 | Heart Defects, Congenital |
| D000086382 | COVID-19 |
| ID | Term |
|---|---|
| D018376 | Cardiovascular Abnormalities |
| D002318 | Cardiovascular Diseases |
| D006331 | Heart Diseases |
| D000013 | Congenital Abnormalities |
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| Dr. Adeline BASQUIN, Rennes |
| UNKNOWN |
| Dr. Nicolas COMBES, Toulouse | UNKNOWN |
| Dr. Xavier IRIART, Bordeaux | UNKNOWN |
| Dr. Daniela LAUX, Paris | UNKNOWN |
| Dr. Magalie LADOUCEUR, Paris | UNKNOWN |
| Pr. BERTRAND LEOBON, Toulouse | UNKNOWN |
| Pr. Caroline OVAERT, Marseille | UNKNOWN |
| Dr. Karine WARIN-FRESSE, Nantes | UNKNOWN |
| Alexis BLANC, Montpellier | UNKNOWN |
| Pr. Roland HENAINE, Lyon | UNKNOWN |
| Hamouda ABASSI, Montpellier | UNKNOWN |
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| through study completion, an average of 2 weeks |
| Other complications | Other complications | through study completion, an average of 2 weeks |
| Number of deaths | Number of deaths | through study completion, an average of 2 weeks |
| 32171076 | Background | Zhou F, Yu T, Du R, Fan G, Liu Y, Liu Z, Xiang J, Wang Y, Song B, Gu X, Guan L, Wei Y, Li H, Wu X, Xu J, Tu S, Zhang Y, Chen H, Cao B. Clinical course and risk factors for mortality of adult inpatients with COVID-19 in Wuhan, China: a retrospective cohort study. Lancet. 2020 Mar 28;395(10229):1054-1062. doi: 10.1016/S0140-6736(20)30566-3. Epub 2020 Mar 11. |
| 32167524 | Background | Wu C, Chen X, Cai Y, Xia J, Zhou X, Xu S, Huang H, Zhang L, Zhou X, Du C, Zhang Y, Song J, Wang S, Chao Y, Yang Z, Xu J, Zhou X, Chen D, Xiong W, Xu L, Zhou F, Jiang J, Bai C, Zheng J, Song Y. Risk Factors Associated With Acute Respiratory Distress Syndrome and Death in Patients With Coronavirus Disease 2019 Pneumonia in Wuhan, China. JAMA Intern Med. 2020 Jul 1;180(7):934-943. doi: 10.1001/jamainternmed.2020.0994. |
| D009358 | Congenital, Hereditary, and Neonatal Diseases and Abnormalities |
| D011024 | Pneumonia, Viral |
| D011014 | Pneumonia |
| D012141 | Respiratory Tract Infections |
| D007239 | Infections |
| D014777 | Virus Diseases |
| D018352 | Coronavirus Infections |
| D003333 | Coronaviridae Infections |
| D030341 | Nidovirales Infections |
| D012327 | RNA Virus Infections |
| D008171 | Lung Diseases |
| D012140 | Respiratory Tract Diseases |