Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Patients with COVID-19 in the Intensive Care Unit (ICU) or hospitalized with severe form have a poor prognosis (almost 30% rate of death). They present often a high cardiovascular risk profile (almost 30% of hypertension and 19% of diabetes). Troponin has been described to be elevated in a high proportion of patients (one fifth of all patients and 50% of non-survivors) suggesting the possibility of cardiomyopathies. High levels of DDimers (81% of non survivors) and fibrin degradation products are also associated with increased risk of mortality suggesting also the possibility of venous thromboembolism. Therefore, screening for cardiomyopathies and venous thromboembolism could represent an important challenge for patients with COVID-19 management.
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Patients with cardiovascular complications | Patients presenting with cardiomyopathies or venous thromboembolism | ||
| Patients without cardiovascular complications | Patients without cardiomyopathies or venous thromboembolism | ||
| Intensive Care Unit patients | Patients admitted in intensive care unit | ||
| Hospital Ward patients | Patients admitted in hospital ward |
Not provided
| Measure | Description | Time Frame |
|---|---|---|
| Determine the incidence of cardiomyopathies and venous thromboembolism | Incidence of cardiomyopathies and/or venous thromboembolism at day 28 | 28 days |
| Measure | Description | Time Frame |
|---|---|---|
| Mortality | Incidence of mortality at day 28 | 28 days |
| Duration of mechanical ventilation | Number of day of using mechanical ventilation for each patients |
Not provided
Inclusion Criteria:
- All consecutive patients with COVID-19 infection admitted to the ICU or hospitalized because of severe form (eg: hypoxia, orthopnea, pneumonitis, kidney insufficiency) will be included
Exclusion Criteria:
- Patients under 18 years
Not provided
Not provided
Not provided
Not provided
Intensive care unit, hospital ward
Not provided
| Name | Affiliation | Role |
|---|---|---|
| Denis DOYEN | CHU de NICE - Archet 1 | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Centre Hospitalier de Cannes | Cannes | 06400 | France | |||
| CHU de Dijon |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 38261092 | Derived | Jozwiak M, Dupuis C, Denormandie P, Aurenche Mateu D, Louchet J, Heme N, Mira JP, Doyen D, Dellamonica J. Right ventricular injury in critically ill patients with COVID-19: a descriptive study with standardized echocardiographic follow-up. Ann Intensive Care. 2024 Jan 23;14(1):14. doi: 10.1186/s13613-024-01248-8. | |
| 37986157 | Derived |
Not provided
Not provided
no data sharing plan has been established.
Not provided
Not provided
Not provided
Not provided
Not provided
| ID | Term |
|---|---|
| D054058 | Acute Coronary Syndrome |
| D009203 | Myocardial Infarction |
| D009205 | Myocarditis |
| D054556 | Venous Thromboembolism |
| D020246 | Venous Thrombosis |
| D011655 | Pulmonary Embolism |
| ID | Term |
|---|---|
| D017202 | Myocardial Ischemia |
| D006331 | Heart Diseases |
| D002318 | Cardiovascular Diseases |
| D014652 | Vascular Diseases |
Not provided
Not provided
Not provided
Not provided
Not provided
whole blood
| hospitalisation duration |
| Shock | Incidence of shock during hospitalisation | hospitalisation duration |
| length of stay | Number of day at hospital | hospitalisation duration |
| Mechanical ventilation | Setting up or not of mechanical ventilation | hospitalisation duration |
| Renal replacement therapy | Administration or not of renal replacement therapy | hospitalisation duration |
| Dijon |
| France |
| Centre Hospitalier de Draguignan | Draguignan | 83300 | France |
| Centre Hospitalier de Grasse | Grasse | 06130 | France |
| Clinique Ambroise-Paré | Neuilly | France |
| CHU de Nice | Nice | 06200 | France |
| Hôpitaux Universitaires Paris Centre - Hôpital Cochin | Paris | 75014 | France |
| CHU de REIMS | Reims | France |
| Jozwiak M, Doyen D, Denormandie P, Goury A, Marey J, Pene F, Cariou A, Mira JP, Dellamonica J, Nguyen LS. Impact of sex differences on cardiac injury in critically ill patients with COVID-19. Respir Res. 2023 Nov 20;24(1):292. doi: 10.1186/s12931-023-02581-5. |
| 32972320 | Derived | Ferrari E, Sartre B, Squara F, Contenti J, Occelli C, Lemoel F, Levraut J, Doyen D, Dellamonica J, Mondain V, Chirio D, Risso K, Cua E, Orban JC, Ichai C, Labbaoui M, Mossaz B, Moceri P, Appert-Flory A, Fischer F, Toulon P. High Prevalence of Acquired Thrombophilia Without Prognosis Value in Patients With Coronavirus Disease 2019. J Am Heart Assoc. 2020 Nov 3;9(21):e017773. doi: 10.1161/JAHA.120.017773. Epub 2020 Sep 25. |
| D007238 |
| Infarction |
| D007511 | Ischemia |
| D010335 | Pathologic Processes |
| D013568 | Pathological Conditions, Signs and Symptoms |
| D009336 | Necrosis |
| D009202 | Cardiomyopathies |
| D013923 | Thromboembolism |
| D016769 | Embolism and Thrombosis |
| D013927 | Thrombosis |
| D008171 | Lung Diseases |
| D012140 | Respiratory Tract Diseases |
| D004617 | Embolism |