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A prospective study of all allergen provocations performed in children at the Hans Christian Andersen Children's Hospital.
The purpose of the study is to investigate the impact of co-morbidities, history, and allergen tests on the outcome of allergen provocation tests.
Subjects are children aged 0-18 years old investigated for allergy to foods or antibiotics. Data entered in the database are demographics, co-morbidities, symptoms, SPT, specific IgE and details of the allergen provocations.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Antibiotics | Children aged 0-18 years investigated for allergy to antibiotics |
| |
| Milk | Children aged 0-18 years investigated for allergy to milk |
| |
| Egg | Children aged 0-18 years investigated for allergy to egg |
| |
| Peanut | Children aged 0-18 years investigated for allergy to peanut |
| |
| Hazelnut | Children aged 0-18 years investigated for allergy to hazelnut |
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| Sesame | Children aged 0-18 years investigated for allergy to sesame |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Oral provocation test | Diagnostic Test | Titrated provocation with allergen |
|
| Measure | Description | Time Frame |
|---|---|---|
| The association of allergy tests with the result of allergen provocation | The value of specific IgE and SPT to predict the outcome of a allergen provocation | 5 years |
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Inclusion Criteria:
clinical suspicion of allergy to foods or antibiotics informed concent -
Exclusion Criteria:
-
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Children referred to the department of pediatrics for investigation of allergy to foods or antibiotics
| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Josefine Gradman, phd | Contact | +4529241375 | josefine.gradman@rsyd.dk | |
| Susanne Halken, DMSc | Contact | susanne.halken@rsyd.dk |
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Hans Christian Andersen Children's Hospital | Recruiting | Odense | Odense C | 5000 | Denmark |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 35719001 | Derived | Gradman J, Petersen BT, Halken S. Oral food challenge with raw egg: Sixty-minute- compared with 30-minute dosing interval. Clin Exp Allergy. 2022 Sep;52(9):1114-1117. doi: 10.1111/cea.14187. Epub 2022 Jul 4. No abstract available. | |
| 32818157 | Derived | Petersen BT, Gradman J. Prospective study of 5-day challenge with penicillins in children. BMJ Paediatr Open. 2020 Aug 4;4(1):e000734. doi: 10.1136/bmjpo-2020-000734. eCollection 2020. |
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| Wheat | Children aged 0-18 years investigated for allergy to wheat |
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| walnut | Children aged 0-18 years investigated for allergy to walnut |
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| cashew | Children aged 0-18 years investigated for allergy to cashew |
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| Pistachio | Children aged 0-18 years investigated for allergy to pistachio |
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| Almond | Children aged 0-18 years investigated for allergy to almond |
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| Soy | Children aged 0-18 years investigated for allergy to soy |
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| Fish | Children aged 0-18 years investigated for allergy to fish |
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| Shellfish | Children aged 0-18 years investigated for allergy to shellfish |
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| Poppy seed | Children aged 0-18 years investigated for allergy to poppy seed |
|