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| ID | Type | Description | Link |
|---|---|---|---|
| 2019-A01839-48 | Other Identifier | IDRCB |
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The perspective of the patient is defined by the patient reported outcomes (PROs). This is a main part of the care in psoriatic arthritis. However , PROs can be influenced by environmental parameters.
Ultrasound represents an objective instrument in the context of psoriatic rheumatism (RhPso) care because it measures inflammatory activity and structural damage at joint and periarticular level.
it is the first study to evaluate the role of inflammatory and structural ultrasound abnormalities as a cause of modification of the patient's perspective measured by PROs in patients with RhPso.
It is an interventional study. Patients will be enrolled in the rheumatology department Of Ambroise Paré Hospital in collaboration with the dermatology departments of the hospital.
All patients with psoriatic arthritis, beginner or established, or patients with psoriasis suspecting the beginning of rheumatism who will consult or are already followed in those departments and give their approval for the study will undergo
Those assessment will be made the same day of their consult in one those departments. They will be asked to complete questionnaires (PROs) on the overall assessment of the disease, pain, quality of life, tiredness, physical limitation / disability and the impact of the disease.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Beginner psoriatic arthritis patients | Other | Every patients consulting in dermatologic or rheumatologic department for a skin psoriasis with clinical symptoms which may lead to the suspicion of psoriatic arthritis |
|
| Confirmed psoriatic arthritis patients | Other | Every patients with psoriatic arthritis followed in rheumatologic department |
|
| Rheumatoid arthritis or Digital osteoarthritis patients | Other | Followed in rheumatologic department |
|
| Skin psoriasis patients without any articular symptoms | Other |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| General evaluation | Other | Demographic characteristic, psoriasis duration, disease duration, treatments |
|
| Measure | Description | Time Frame |
|---|---|---|
| Evaluation of patient global assessment (PGA) in patients with Psoriatic Arthritis | The study of patient global assessment will permit to understand the impact of inflammation and external structural damage measured by ultrasound in patients with psoriatic arthritis (newly diagnosed or with confirmed diagnosis). At enrollment visit (only visit) of patient PGA will be assessed with a digital scale from 0 to 10 | 1 day |
| Measure | Description | Time Frame |
|---|---|---|
| Evaluation of the impact of inflammation and external structural damage measured by ultrasound | Evaluate the impact of inflammation and external structural damage measured by ultrasound to explain the others PROs: PGA joint damage activity and cutaneous damage will be measure with a digital scale | 1 day |
| Evaluation of the impact of inflammation and external structural damage measured by ultrasound |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Maria-Antonietta D'AGOSTINO, PhD | Contact | +331 49 09 56 74 | maria-antonietta.dagostino@aphp.fr |
| Name | Affiliation | Role |
|---|---|---|
| Maria-Antonietta D'AGOSTINO, PhD | Rheumatology Department, Ambroise Paré Hospital | Principal Investigator |
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ultrasound evaluation will be on masking from clinical evaluation
| Dermatological evaluation | Other | treatment and evaluation |
|
| Rheumatological evaluation | Other | joints, enthesis, tendons, and other ultrasound abnormalities |
|
| para clinical data | Other | biological data, medical imaging data |
|
| Patient reported outcomes (PROs) | Other | Psoriatic arthritis impact of disease 12 (PsAID12), hospital anxiety and depression scale (HAD), SF 36 |
|
Evaluate the impact of inflammation and external structural damage measured by ultrasound to explain the others PROs: Pain will be assessed with a digital scale |
| 1 day |
| Evaluation of the impact of inflammation and external structural damage measured by ultrasound | Evaluate the impact of inflammation and external structural damage measured by ultrasound to explain the others PROs: Physical limitation/ disability will be assessed with the health assessment questionnaire (HAQ) | 1 day |
| Evaluation of the impact of inflammation and external structural damage measured by ultrasound | Evaluate the impact of inflammation and external structural damage measured by ultrasound to explain the others PROs: Quality of life will be assessed with a short form-36 (SF-36) questionnaire | 1 day |
| Evaluation of the impact of inflammation and external structural damage measured by ultrasound | Evaluate the impact of inflammation and external structural damage measured by ultrasound to explain the others PROs: Disease effect will be assessed with psoriatic arthritis impact of disease (PsAID) 12 questionnaire | 1 day |
| Evaluation of the impact of inflammation and external structural damage measured by ultrasound | Evaluate the impact of inflammation and external structural damage measured by ultrasound to explain the others PROs: Fatigue will be assessed with a digital scale | 1 day |
| Evaluation of the impact of inflammation and external structural damage measured by ultrasound | Compare the results( prevalence of ultrasound irregularity, PROs, and factor which explain PROs) to people who suffer from psoriatic, without damage, without sign of joints damages or rheumatoid arthritis (RA) or digital osteoarthritis. Ultrasound damages: Synovitis, tenosynovitis, enthesitis, dactylitis, erosions, periosteal appositions ( enthesophytes, osteophyte and bony cortical irregularity) will be defined according to established by outcome measures in rheumatology (OMERACT) definitions and rating according to scores established by OMERACT | 1 day |
| ID | Term |
|---|---|
| D015535 | Arthritis, Psoriatic |
| ID | Term |
|---|---|
| D025242 | Spondylarthropathies |
| D025241 | Spondylarthritis |
| D013166 | Spondylitis |
| D013122 | Spinal Diseases |
| D001847 | Bone Diseases |
| D009140 | Musculoskeletal Diseases |
| D001168 | Arthritis |
| D007592 | Joint Diseases |
| D011565 | Psoriasis |
| D017444 | Skin Diseases, Papulosquamous |
| D012871 | Skin Diseases |
| D017437 | Skin and Connective Tissue Diseases |
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| ID | Term |
|---|---|
| D000071066 | Patient Reported Outcome Measures |
| ID | Term |
|---|---|
| D019538 | Health Care Surveys |
| D011795 | Surveys and Questionnaires |
| D003625 | Data Collection |
| D004812 | Epidemiologic Methods |
| D008919 | Investigative Techniques |
| D006302 | Health Services Research |
| D006285 | Health Planning |
| D004472 | Health Care Economics and Organizations |
| D063868 | Patient Outcome Assessment |
| D017063 | Outcome Assessment, Health Care |
| D010043 | Outcome and Process Assessment, Health Care |
| D011787 | Quality of Health Care |
| D006298 | Health Services Administration |
| D017530 | Health Care Quality, Access, and Evaluation |
| D017531 | Health Care Evaluation Mechanisms |
| D011634 | Public Health |
| D004778 | Environment and Public Health |
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