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Induction of labour (IOL) is done for 20% of pregnancies for various maternal and fetal indications and nearly 20% of labour inductions end up in caesarean section. The most common causes are failed induction and intrapartum fetal distress. In spite of significant advances in methods of IOL and intrapartum fetal monitoring, no interventions are proven to reduce the development of intrapartum fetal distress
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| study group | Experimental | 50 mg oral sildenafil citrate tablet |
|
| placebo group | Placebo Comparator | placebo tablets of the same shape, color and size of sildenafil citrate tablets |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Sildenafil 50 mg | Drug | 50 mg oral Sildenafil tablet |
| |
| Placebo oral tablet |
| Measure | Description | Time Frame |
|---|---|---|
| The rate of cesarean section for intrapartum fetal distress | Fetus will be considered to be distressed if Ominous fetal heart rate changes led to cesarean section was present | 24 hours |
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Inclusion Criteria:
Exclusion Criteria:
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Ahmed Abbas | Assiut | Cairo Governorate | 002 | Egypt |
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| ID | Term |
|---|---|
| D005316 | Fetal Distress |
| ID | Term |
|---|---|
| D012816 | Signs and Symptoms |
| D013568 | Pathological Conditions, Signs and Symptoms |
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| ID | Term |
|---|---|
| D000068677 | Sildenafil Citrate |
| ID | Term |
|---|---|
| D013449 | Sulfonamides |
| D000577 | Amides |
| D009930 | Organic Chemicals |
| D013450 | Sulfones |
| D013457 |
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| Drug |
placebo tablets of the same shape, color and size of Sildenafil tablets manufactured in the Department of Pharmaceuticals, Faculty of Pharmacy |
|
| Sulfur Compounds |
| D010879 | Piperazines |
| D006573 | Heterocyclic Compounds, 1-Ring |
| D006571 | Heterocyclic Compounds |
| D011687 | Purines |
| D006574 | Heterocyclic Compounds, 2-Ring |
| D000072471 | Heterocyclic Compounds, Fused-Ring |