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| Name | Class |
|---|---|
| University of Palermo | OTHER |
| University of Pavia | OTHER |
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We sought to investigate the effects of 4 weeks of 16/8 time restricted eating (TRE) with windows of 16 hours of fasting and 8 hours of eating) on elite cyclists' performance, metabolic and blood parameters.
Sixteen elite under-23 cyclists were randomly assigned to a TRE group or to a control group (CTRL) with a traditional meal pattern. The TRE group consumed 100% of its estimated daily energy needs in an 8-hour time window: from 10:00 AM (ante meridiem) to 6:00 PM (post meridiem) whilst the CTRL group consumed 100% of its estimated daily energy needs in 3 meals between 7:00 AM and 9:00 PM. During the experimental period, training loads were similar in the two groups. Athletes were tested before and after 4 weeks of the intervention. Body composition , basal metabolism, performances indexes and blood parameters were measured.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Time restricted eating (TRE) | Experimental | TRE group consumed 100% of its estimated daily energy needs in an 8-hour time window: from 10:00 AM to 6:00 PM |
|
| Control (CTRL) | Active Comparator | CTRL group consumed 100% of its estimated daily energy needs in 3 meals between 7:00 AM and 9:00 PM |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Time restricted eating | Other | TRE group consumed 100% of its estimated daily energy needs in an 8-hour time window: from 10:00 AM to 6:00 PM |
|
| Measure | Description | Time Frame |
|---|---|---|
| VO2max | Maximal oxygen consumption (in ml O2/Kg/min) measured during a cycloergometer incremental test through a gas analyses | 4 weeks |
| fat mass | fat mass measured through body impedence analyser | 4 weeks |
| lean body mass | lean body mass mass measured through body impedence analyser | 4 weeks |
| Measure | Description | Time Frame |
|---|---|---|
| white blood cells | white blood cells as thousands per microliter | 4 weeks |
| Eosinophils | Eosinophils as percentage of total white blood cells |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Affiliation | Role |
|---|---|---|
| Antonio Paoli, MD | University of Padova | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Nutrition and Exercise Lab, DSB, University of Padova | Padova | 35131 | Italy |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 30925707 | Result | Paoli A, Tinsley G, Bianco A, Moro T. The Influence of Meal Frequency and Timing on Health in Humans: The Role of Fasting. Nutrients. 2019 Mar 28;11(4):719. doi: 10.3390/nu11040719. | |
| 27737674 | Result | Moro T, Tinsley G, Bianco A, Marcolin G, Pacelli QF, Battaglia G, Palma A, Gentil P, Neri M, Paoli A. Effects of eight weeks of time-restricted feeding (16/8) on basal metabolism, maximal strength, body composition, inflammation, and cardiovascular risk factors in resistance-trained males. J Transl Med. 2016 Oct 13;14(1):290. doi: 10.1186/s12967-016-1044-0. |
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| ID | Term |
|---|---|
| D005215 | Fasting |
| D000093763 | Intermittent Fasting |
| ID | Term |
|---|---|
| D005247 | Feeding Behavior |
| D001519 | Behavior |
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It is a single blind, parallel arms study
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Outcome assessor treated anonymus data
|
| Control | Other | CTRL group consumed 100% of its estimated daily energy needs in 3 meals between 7:00 AM and 9:00 PM |
|
|
| 4 weeks |
| Monocytes | Monocytes as percentage of total white blood cells | 4 weeks |
| Basophiles | Basophiles s percentage of total white blood cells | 4 weeks |
| Hematocrit | Hematocrit as percentage | 4 weeks |
| Haemoglobin | Haemoglobin as gram per Liter | 4 weeks |
| Mean cell volume | mean cell volume as femtonLiter | 4 weeks |
| mean cell haemoglobin | mean cell haemoglobin as picograms | 4 weeks |
| ESR (Erythrocyte sedimentation rate ) | ESR as millimeters per hour | 4 weeks |
| CRP (C-reactive protein) | CRP as milligram per deciliter | 4 weeks |
| Total cholesterol | Total cholesterol as milligram per deciliter | 4 weeks |
| TG (triglycerides) | TG as milligram per deciliter | 4 weeks |
| glucose | glucose as milligram per deciliter | 4 weeks |
| creatinine | creatinine as milligram per deciliter | 4 weeks |
| creatin kinase | creatin kinase as milligram per deciliter | 4 weeks |
| iron | iron as microgram per deciliter | 4 weeks |
| ferritin | ferritin as microgram per liter | 4 weeks |
| transferrin | ferritin as milligram per deciliter | 4 weeks |
| TSH (Thyroid Stimulating Hormone) | TSH as micro international unit per milliliter | 4 weeks |
| T3 (triiodothyronine) free | T3 free as picogram per milliliter | 4 weeks |
| Testosterone free | Testosterone free as picogram per milliliter | 4 weeks |
| IL-6 | IL-6 as picogram per milliliter | 4 weeks |
| TNFalfa | TNFalfa as picogram per milliliter | 4 weeks |
| IGF-1 | IGF-1 as nanogram per milliliter | 4 weeks |
| Insulin | Insulin micro international unit per milliliter | 4 weeks |
| 27550719 | Result | Tinsley GM, Forsse JS, Butler NK, Paoli A, Bane AA, La Bounty PM, Morgan GB, Grandjean PW. Time-restricted feeding in young men performing resistance training: A randomized controlled trial. Eur J Sport Sci. 2017 Mar;17(2):200-207. doi: 10.1080/17461391.2016.1223173. Epub 2016 Aug 22. |
| 31268131 | Result | Tinsley GM, Moore ML, Graybeal AJ, Paoli A, Kim Y, Gonzales JU, Harry JR, VanDusseldorp TA, Kennedy DN, Cruz MR. Time-restricted feeding plus resistance training in active females: a randomized trial. Am J Clin Nutr. 2019 Sep 1;110(3):628-640. doi: 10.1093/ajcn/nqz126. |
| 33308259 | Derived | Moro T, Tinsley G, Longo G, Grigoletto D, Bianco A, Ferraris C, Guglielmetti M, Veneto A, Tagliabue A, Marcolin G, Paoli A. Time-restricted eating effects on performance, immune function, and body composition in elite cyclists: a randomized controlled trial. J Int Soc Sports Nutr. 2020 Dec 11;17(1):65. doi: 10.1186/s12970-020-00396-z. |