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Adhesive small bowel obstruction (ASBO) is one of the most common complications and is a major cause of admission after intra-abdominal surgery. To date, the ideal management of ASBO remains controversial. The aim of this protocol designed as a double-blind randomized controlled trial is to investigate the efficacy of laser acupuncture (LA) therapy in patients with ASBO.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| LA group | Experimental | The subjects in the experimental group will receive 0.375 J of energy at each of the following acupoints: LI4 (Hegu, B3), PC6 (Neiguan, B3), ST25 (Tianshu, B3), ST36 (Zusanli, B2), CV4 (Guanyuan), CV12 (Zhongwan, B3). |
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| Control group | Sham Comparator | The subjects in the control group will receive sham LA treatment, without any laser output (no stimulation) at the same acupoints used in experimental group. |
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| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Laser acupuncture | Procedure | Laser acupuncture is a non-invasive therapy that involves stimulation of traditional acupoints with low-intensity, non-thermal laser irradiation. |
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| Measure | Description | Time Frame |
|---|---|---|
| Success rate of conservative treatment | Defined as no need for long term nasogastric tube decompression and operative intervention. | 2 week |
| Measure | Description | Time Frame |
|---|---|---|
| Time to oral intake | Defined as participants can try intake due to symptoms improved including nausea, vomiting, distension and pain. | 2 weeks |
| Length of hospital stay | Date from admission to discharge |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Chun-Ting Liu, MD | Contact | +886-7-7317123 | 2334 | juntin0214@gmail.com |
| Name | Affiliation | Role |
|---|---|---|
| Chun-Ting Liu, MD | Department of Chinese Medicine, Kaohsiung Chang Gung Memorial Hospital | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Kaohsiung Chang Gung Memorial Hospital | Recruiting | Kaohsiung City | 833 | Taiwan |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 33655978 | Derived | Shih CH, Hsieh TM, Wu BY, Liu CT. Effect of laser acupuncture on adhesive small bowel obstruction: A prospective double-blind randomized controlled trial. Medicine (Baltimore). 2021 Mar 5;100(9):e25035. doi: 10.1097/MD.0000000000025035. |
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The participants in each group will receive real (with energy output) or sham (without energy output) laser acupuncture. The feelings of participants in each group are not different. The care provider and outcomes assessor don't involve the random allocation and don't know if participants receive real laser acupuncture.
| Through study completion, an average of 1 year |
| Serum lipase | Serum lipase | Up to 2 weeks |
| Serum amylase | Serum amylase | Up to 2 weeks |
| Serum cortisol | Serum cortisol | Up to 2 weeks |
| Serum motilin | Serum motilin | Up to 2 weeks |
| Serum ghrelin | Serum ghrelin | Up to 2 weeks |
| Serum intestinal fatty acid binding protein (I-FABP) | Serum intestinal fatty acid binding protein (I-FABP) | Up to 2 weeks |