Evaluation Of Efficacy Of Liquid Platelet Rich Fibrin In Temporomandibular Joint Disorders

Evaluation Of The Clinical Efficacy Of Liquid Platelet Rich Fibrin Application In Painful Temporomandibular Joint Disorders

This randomized clinical trial aims to evaluate the efficacy of liquid platelet-rich fibrin administration at different Wilkes stages.

Thirty six patients with unilateral painful internal derangement (ID) (Wilkes' 3-4-5) were included. Patients were divided into 2 groups. In group 1 were treated with only artrosythesis. In group 2 were treated with artrosythesis and liquid platelet rich fibrin. In group 2, patients were injected with 1.5-2cc of liquid platelet-rich fibrin within the superior joint space at operation day. Pain and subjective dysfunction were recorded using a visual analog scale and Helkimo index at operation day and tenth day, one month later and 3 months later.

Inclusion Criteria:

• Unilateral internal temporomandibular disorder
• localized temporomandibular joint pain
• Scoring 3 and above in Wilke's classification.

Exclusion Criteria:

• Autoimmune diseases
• Significant mechanical obstruction that prevents mouth opening
• Acute capsulitis,
• Benign or malignant temporomandibular joint lesions
• Neurological disorders,
• Blood diseases and coagulation disorders
• Patients with a history of allergies or anaphylactic shock.