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| Name | Class |
|---|---|
| Foundation for Physical Medicine and Rehabilitation | OTHER |
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A prospective, observational study assessing the relationship between HbA1c level and the post-injection blood glucose signature. Participants will be non-diabetic, pre-diabetic, non-insulin dependent and insulin dependent type 2 diabetic patients who will be receiving a knee steroid injection. All of them will be consented a week prior to the injection, when the CGM sensor will be applied to the back of the upper arm. This will be removed a week after the injection. KOOS survey as well as VAS will be administered. Adverse events (e.g., change in medication or hospitalization) will be monitored throughout the study.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Diabetic with Knee Osteoarthritis | HbA1c between 6.5% - 12.0% in the 3 months prior to Visit 1 |
| |
| Pre-diabetic with Knee Osteoarthritis | HbA1c between 5.6% - 6.4% in the 3 months prior to Visit 1 |
| |
| Non-diabetic with Knee Osteoarthritis | HbA1c < 5.6% in the 3 months prior to Visit 1 |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| 40 mg Triamcinolone acetonide | Drug | Unilateral knee steroid injection |
|
| Measure | Description | Time Frame |
|---|---|---|
| Post-injection glucose levels | Blood glucose levels after injection of steroid to the knee | 1 week |
| Measure | Description | Time Frame |
|---|---|---|
| Post-injection adverse events | Adverse events after injection of steroid to the knee | 1 week |
| KOOS Knee survey | KOOS Knee survey administered before and after steroid injection to the knee |
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Inclusion Criteria:
Exclusion Criteria:
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Knee joint osteoarthritis requiring knee joint steroid injection
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Parkland Hospital | Dallas | Texas | 75235 | United States |
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| ID | Term |
|---|---|
| D003920 | Diabetes Mellitus |
| D020370 | Osteoarthritis, Knee |
| ID | Term |
|---|---|
| D044882 | Glucose Metabolism Disorders |
| D008659 | Metabolic Diseases |
| D009750 | Nutritional and Metabolic Diseases |
| D004700 | Endocrine System Diseases |
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| ID | Term |
|---|---|
| D014222 | Triamcinolone Acetonide |
| ID | Term |
|---|---|
| D014221 | Triamcinolone |
| D011245 | Pregnadienes |
| D011278 | Pregnanes |
| D013256 | Steroids |
| D000072473 |
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| 2 weeks |
| D010003 | Osteoarthritis |
| D001168 | Arthritis |
| D007592 | Joint Diseases |
| D009140 | Musculoskeletal Diseases |
| D012216 | Rheumatic Diseases |
| Fused-Ring Compounds |
| D011083 | Polycyclic Compounds |
| D013259 | Steroids, Fluorinated |