Texture Features and PDL1 in CT-PET 18 FDG

Correlation Between Texture Features With CT-PET 18 FDG and Overexpression of PDL1 in Non-small-cell Lung Carcinomas During the Initial Staging.

Search correlation between texture features in CT-PET 18 FDG and overexpression of PDL1 in non-small cell lung carcinomas during the inital staging.

The hypothesis is that overexpression of PDL1is correlated with at least one texture feature among those selected.

84 CT-PET 18 FDG at the initial staging of a non small cell lung carcinoma (adenocarcinoma or squamous cell carcinoma), whose the biopsed site was the primitive site or the drainage lymphadenopathy, without previous treatment, were recruited and analyzed by a software allowing to estimate texture features.

Inclusion criteria:

• adult patient ;
• first CT-PET 18 FDG realized for the inital staging ;
• absence of previous treatment for a thoracic neoplasm ;
• biopsy realized on the primitive site or local drainage lymphadenopathy ;
• primitive site viewable with morphological imagery ;
• availability of evaluation of PDL1's overexpression ;

Exclusion criteria

- Refusal to participate in this research