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Autism Spectrum Disorder (ASD) is a neurodevelopmental disorder with characteristic deficits in social functioning and presence of stereotypic behavior. Several research studies have examined potential deficits in cognitive skills, such as working memory, in this condition. A meta-analysis of the studies aimed at evaluating working memory (WM) in autistic population suggested deficits in visual and verbal aspects of WM. Working memory training has also been studied in other neurodevelopmental disorders such as Attention Deficit Hyperactivity Disorder (ADHD). The study includes development of mobile-based games for training WM and other cognitive skills in patients and the evaluation of such training in reducing symptoms of ASD. These games may also be useful for other neurodevelopmental disorders.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Game-based training | Experimental | Participants play games for cognitive training |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Game-based cognitive training | Behavioral | A suite of 5 games is presented to the participants for training working memory |
|
| Measure | Description | Time Frame |
|---|---|---|
| Corsi Task Block Span | It is an indicator of working memory. The value ranges between 0 and 9. Higher values mean better outcome. | change from baseline to program completion or last usage (up to 30 days of usage within 56-day trial period from the first day of data collection) |
| Corsi Task Total Score | It is an indicator of working memory. The minimum value is 0, the maximum value has no limit. Higher values mean better outcome. | change from baseline to program completion or last usage (up to 30 days of usage within 56-day trial period from the first day of data collection) |
| Measure | Description | Time Frame |
|---|---|---|
| Autism Treatment Evaluation Checklist Total Score | Autism Treatment Evaluation Checklist is a measure to evaluate treatments for Autism. The total score ranges between 0 and 179. Higher values mean better outcome. | change from baseline to program completion or last usage (up to 30 days of usage within 56-day trial period from the first day of data collection) |
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Indian Institute of Technology Kanpur | Kanpur | Uttar Pradesh | 208016 | India |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 25256627 | Background | de Vries M, Prins PJ, Schmand BA, Geurts HM. Working memory and cognitive flexibility-training for children with an autism spectrum disorder: a randomized controlled trial. J Child Psychol Psychiatry. 2015 May;56(5):566-76. doi: 10.1111/jcpp.12324. Epub 2014 Sep 26. |
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| ID | Term |
|---|---|
| D000067877 | Autism Spectrum Disorder |
| ID | Term |
|---|---|
| D002659 | Child Development Disorders, Pervasive |
| D065886 | Neurodevelopmental Disorders |
| D001523 | Mental Disorders |
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