The investigators studied the benefit of preoperative autologous blood donation in participants who undergo total hip arthroplasty. Study is made as a prospective and randomized.

Total hip arthroplasty is procedure followed with large perioperative and postoperative blood loss. In order to avoid the application of large amounts of allogeneic blood, preoperative autologous blood donation as a tipe of autologous transfusion have been developed.

In this study, the investigators studied the benefit of preoperative autologous blood donation in participants who undergo total hip arthroplasty. Study is made as a prospective and randomized.

Participants were divided into three groups: the first group donated one dose of autologous blood 14 days preoperatively, the second group donated one dose of autologous blood 72 hours preoperatively and a third group was not donated autologous blood.

The blood parameters, hemodynamic stability, bleeding, the need for application of autologous or homologous blood and length of hospital stay were compared.

Inclusion Criteria:

• subject older than 18 years
• subject has primary coxarthrosis
• subject has indication for total hip replacement

Exclusion Criteria:

• subject has secondary coxarthrosis
• subject has need for revision endoprosthesis
• history of autoimmune, malignancy or coagulation disorder
• history of myocardial infarct or cerebrovascular insult in last 6 months
• history of angina pectoris and unregulated hypertension
• history of renal or liver failure