The Association of hsCRP and Radiotherapy-Induced Toxicity in Patients With Nasopharyngeal Carcinoma

An Explorative Study on the Association of High Sensitivity C-Reactive Protein (hsCRP) and Radiotherapy-Induced Toxicity in Patients With Nasopharyngeal Carcinoma

The primary purpose of this study is to explore the association of high sensitivity C-reactive protein (hsCRP) and radiotherapy(RT)-induced toxicity in patients with nasopharyngeal carcinoma. In each patient, hsCRP levels in the pre- and post-RT plasma samples will be measured according to the schedule we set.

Inclusion Criteria:

• Patients were pathologically newly diagnosed with nasopharyngeal carcinoma and had no previous history of other tumors
• According to the treatment strategies of doctors, patients need to receive radiotherapy with or without chemotherapy (for example, neoadjuvant chemotherapy, concurrent chemotherapy, adjuvant chemotherapy) or targeted therapy
• Willingness to sign the informed consent and return to enrolling institution for follow-up and data collection

Exclusion Criteria:

• Patients do not conform to the inclusion criteria
• Pregnant or Nursing women
• Men or women of childbearing potential who are unwilling to employ adequate contraception
• Vital organs dysfunction(for example, kidneys, heart, liver, lungs, brain)
• Other contraindications or unsuitable conditions for radiotherapy