Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Establish if change from the baseline in ultrasound muscle parameters over 2 months of rehabilitation correlates with functional status of SCI patients at the end of rehabilitation
Rehabilitation is the key to ambulatory recovery in patients with spinal cord injury, although only 25% of patients regain this ability despite current rehabilitation protocols. There is emerging evidence that intensive and prolonged rehabilitation, though costly and manpower intensive, may result in ambulatory recovery in patients previously thought to be non-ambulant. However, there are no suitable clinical biomarkers which can identify these group of patients who will benefit from this intervention.
Hence the aim is to establish if change from the baseline in ultrasound muscle parameters over rehabilitation correlates with functional status of SCI patients.
Not provided
Not provided
Not provided
Not provided
Not provided
| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Muscle ultrasound | Experimental | Muscle ultrasound will be performed for the patient on admission and at 1-2 months from inpatient rehabilitation. |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Muscle ultrasound | Diagnostic Test | The muscle thickness and muscle quality will be assessed on ultrasound |
|
| Measure | Description | Time Frame |
|---|---|---|
| Functional Independence Score | An 18-item of physical, psychological and social function (graded from 1-7) | Baseline (Performed on admission to inpatient rehabilitation) |
| Functional Independence Score | An 18-item of physical, psychological and social function (graded from 1-7) | Performed at 1-2 months after starting rehabilitation |
| Functional Independence Score | An 18-item of physical, psychological and social function (graded from 1-7) | Performed at 3-6 months |
| Functional Independence Score | An 18-item of physical, psychological and social function (graded from 1-7) | Performed at 1 year |
| Spinal Cord Independence Measure (SCIM) III | It is used by health care practitioners to assess and grade the functional status of a person based on the level of assistance he or she requires, in patients with spinal cord injury. Only the patient's indoor mobility subscore will be assessed from abilities, graded from 0-8. | Baseline (Performed on admission to inpatient rehabilitation) |
| Spinal Cord Independence Measure (SCIM) III | It is used by health care practitioners to assess and grade the functional status of a person based on the level of assistance he or she requires, in patients with spinal cord injury. Only the patient's indoor mobility subscore will be assessed from abilities, graded from 0-8. | Performed at 1-2 months after starting rehabilitation |
| Measure | Description | Time Frame |
|---|---|---|
| Range of motion of elbow, hip and knee | Range of motion of elbow, hip and knee | Baseline (Performed on admission to inpatient rehabilitation) |
| Range of motion of elbow, hip and knee | Range of motion of elbow, hip and knee |
Not provided
Inclusion Criteria:
Exclusion Criteria:
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
| Name | Affiliation | Role |
|---|---|---|
| Matthew Tay, MD | Tan Tock Seng Hospital | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Tan Tock Seng Hospital Rehabilitation Centre | Singapore | 569766 | Singapore |
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
| ID | Term |
|---|---|
| D013119 | Spinal Cord Injuries |
| ID | Term |
|---|---|
| D013118 | Spinal Cord Diseases |
| D002493 | Central Nervous System Diseases |
| D009422 | Nervous System Diseases |
| D020196 | Trauma, Nervous System |
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
| Spinal Cord Independence Measure (SCIM) III | It is used by health care practitioners to assess and grade the functional status of a person based on the level of assistance he or she requires, in patients with spinal cord injury. Only the patient's indoor mobility subscore will be assessed from abilities, graded from 0-8. | Performed at 3-6 months |
| Spinal Cord Independence Measure (SCIM) III | It is used by health care practitioners to assess and grade the functional status of a person based on the level of assistance he or she requires, in patients with spinal cord injury. Only the patient's indoor mobility subscore will be assessed from abilities, graded from 0-8. | Performed at 1 year |
| ASIA score | This is an assessor administered test that systematically examines the dermatomes and myotomes in spinal cord patients through testing the strength and sensation | Baseline (Performed on admission to inpatient rehabilitation) |
| ASIA score | This is an assessor administered test that systematically examines the dermatomes and myotomes in spinal cord patients through testing the strength and sensation | Performed at 1-2 months after starting rehabilitation |
| ASIA score | This is an assessor administered test that systematically examines the dermatomes and myotomes in spinal cord patients through testing the strength and sensation | Performed at 3-6 months |
| ASIA score | This is an assessor administered test that systematically examines the dermatomes and myotomes in spinal cord patients through testing the strength and sensation | Performed at 1 year |
| Walking Index for Spinal Cord Injury II (WISCI II) | A walking scale used by health care practitioners to grade the walking ability of SCI patients. | Baseline (Performed on admission to inpatient rehabilitation) |
| Walking Index for Spinal Cord Injury II (WISCI II) | A walking scale used by health care practitioners to grade the walking ability of SCI patients. | Performed at 1-2 months after starting rehabilitation |
| Walking Index for Spinal Cord Injury II (WISCI II) | A walking scale used by health care practitioners to grade the walking ability of SCI patients. | Performed on 3-6 months |
| Walking Index for Spinal Cord Injury II (WISCI II) | A walking scale used by health care practitioners to grade the walking ability of SCI patients. | Performed on 1 year |
| Performed at 1-2 months after starting rehabilitation |
| Range of motion of elbow, hip and knee | Range of motion of elbow, hip and knee | Performed at 3-6 months |
| Range of motion of elbow, hip and knee | Range of motion of elbow, hip and knee | Performed at 1 year |
| Spasticity | (2) Spasticity of the elbow flexors, knee extensors and ankle plantarflexors using the Modified Ashworth Scale, with a higher score indicating worse spasticity | Baseline (Performed on admission to inpatient rehabilitation) |
| Spasticity | (2) Spasticity of the elbow flexors, knee extensors and ankle plantarflexors using the Modified Ashworth Scale, with a higher score indicating worse spasticity | Performed at 1-2 months after starting rehabilitation |
| Spasticity | (2) Spasticity of the elbow flexors, knee extensors and ankle plantarflexors using the Modified Ashworth Scale, with a higher score indicating worse spasticity | Performed at 3-6 months |
| Spasticity | (2) Spasticity of the elbow flexors, knee extensors and ankle plantarflexors using the Modified Ashworth Scale, with a higher score indicating worse spasticity | Performed at 1 year |
| D014947 | Wounds and Injuries |