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Brucellosis is a common zoonotic infection in many parts of the world including the Mediterranean and Middle Eastern countries.
Neurobrucellosis may develop at any stage of disease and may have widely variable manifestations, including encephalitis, meningoencephalitis, radiculitis, myelitis, peripheral and cranial neuropathies, subarachnoid hemorrhage, and psychiatric manifestations.
Brucellosis is a common zoonotic infection in many parts of the world including the Mediterranean and Middle Eastern countries.
Neurobrucellosis may develop at any stage of disease and may have widely variable manifestations, including encephalitis, meningoencephalitis, radiculitis, myelitis, peripheral and cranial neuropathies, subarachnoid hemorrhage, and psychiatric manifestations.
The aimed is to shed light to the obscure areas of diagnosis in neurobrucellosis and have detailed general and neurologic features
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Neurobrucellosis | Brucellosis associated with neuropsychiatric manifestations |
| |
| Non-neurobrucellosis | Brucellosis not associated with neuropsychiatric manifestations |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| MoCA | Diagnostic Test | Cognitive function was assessed by using MoCA score. Cognitive impairment was considered present when MoCA scores were <26. Maximum score is 30. |
|
| Measure | Description | Time Frame |
|---|---|---|
| MoCA s | Cognitive function was assessed by using MoCA score. Cognitive impairment was considered present when MoCA scores were <26 . | 24 hours |
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Inclusion Criteria:
Exclusion Criteria:
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82 consecutive patients with brucellosis (18 patients with neuropsychiatric manifestations and 64 patients without neuropsychiatric manifestations) were recruited.
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| Name | Affiliation | Role |
|---|---|---|
| Esmael M Ahmed, MD | Assistant Prof of Neurology | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Mansoura University Hospital | Al Mansurah | Egypt |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| Result | Young EJ. Brucella species. In: Mandell GL, Bennett JE, Dolin R, eds. Principles and practice of infectious diseases. 7th ed. Philadelphia: Churchill Livingstone, 2010:2921-5. | ||
| 15930423 | Result | Pappas G, Akritidis N, Bosilkovski M, Tsianos E. Brucellosis. N Engl J Med. 2005 Jun 2;352(22):2325-36. doi: 10.1056/NEJMra050570. No abstract available. | |
| Result | Finn TB. Brucellosis. In: Cohen J, Powderly WG, eds. Infectious diseases. 2nd ed. New York: Elsevier, 2004:1665-9. | ||
| 16647757 |
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| ID | Term |
|---|---|
| D002006 | Brucellosis |
| ID | Term |
|---|---|
| D016905 | Gram-Negative Bacterial Infections |
| D001424 | Bacterial Infections |
| D001423 | Bacterial Infections and Mycoses |
| D007239 | Infections |
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| Result |
| Eren S, Bayam G, Ergonul O, Celikbas A, Pazvantoglu O, Baykam N, Dokuzoguz B, Dilbaz N. Cognitive and emotional changes in neurobrucellosis. J Infect. 2006 Sep;53(3):184-9. doi: 10.1016/j.jinf.2005.10.029. Epub 2006 May 2. |