Efficacy of Deutetrabenazine to Control Symptoms of Dysphagia Associated with HD

Efficacy of Deutetrabenazine in Huntington's Disease Patients with Dysphagia: a Randomised, Placebo-controlled Pilot Study

To determine the efficacy of deutetrabenazine to control symptoms of dysphagia associated with HD.

The primary endpoint is the change in swallow function/dysphagia from baseline to maintenance therapy.

Inclusion Criteria:

• Confirmed diagnosis of HD
• Symptoms of dysphagia
• Must be able to swallow tablets

Exclusion Criteria:

• Other confounding diseases that affect swallowing
• Depression
• Hepatic impairment
• Renal impairment
• Dementia