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Patients undergoing thoracotomy, thoracoscopy or other surgical procedures involving the integrity of the chest wall are always in a special point of interest of both surgical and anesthesiological specialities. Most of the patients will describe the pain after thoracic surgery as severe. It might lead to a number of serious complications: respiratory failure due to splinting; inability to clear secretions by effective coughing, with resulting pneumonia; and turning into a chronic pain: the post-thoracotomy pain syndrome.
Traditional pain management in these groups of patients - such as opiate treatment, thoracic epidural analgesia, and non-opioid drugs - may have serious side effects. Large doses of opiates suppress the cough reflex and lead to respiratory depression with subsequent re-intubation and re-ventilation. Thoracic epidural analgesia, though being considered paramount among other analgesic options, requires a significant clinical experience. Still, it might be insufficient for satisfactory pain control and even complicated with pneumothorax, total spinal anaesthesia and inadvertent intravascular injection. Non-steroidal anti-inflammatory drugs (NSAIDs) and Tramadol are weak analgesics inadequate for severe pain control and might be responsible for gastrointestinal bleeding.
We suggest performing erector spinae plane block for intraoperative and postoperative pain management due to the ease of use and better analgesic effect. What remains is hard proof for the clinical efficacy and safety of this block, followed by a demonstration of the uptake of it in the hands of non-regional anaesthetists.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Thoracic surgery + ESPblock | Experimental | Thoracic surgery + ESPblock + standard pain management |
|
| Abdominal surgery + ESPblock | Experimental | Abdominal surgery + ESPblock + standard pain management |
|
| Spinal surgery + ESPblock | Experimental | Spinal surgery + ESPblock + standard pain management |
|
| Thoracic surgery | No Intervention | Thoracic surgery + standard pain management | |
| Abdominal surgery | No Intervention | Abdominal surgery + standard pain management | |
| Spinal surgery | No Intervention | Spinal surgery + standard pain management |
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Erector spinae plane block | Procedure | Erector spinae plane block |
|
| Measure | Description | Time Frame |
|---|---|---|
| Visual Analog Pain Score | Reported immediate postoperative VAS score, up to 3rd day | 3 days |
| Total pain med consumption in the PACU | Total Morphine, NSAIDs and Tramadol amount (mg) in the PACU | 3 hours |
| Length of stay in the PACU | Length of stay in postoperative care room | 24 hours |
| Measure | Description | Time Frame |
|---|---|---|
| Length of hospital stay | Length of hospital stay | 30 days |
| Chronic pain development | Rate of chronic pain at 3 and 6 months after surgery |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Dmitry Natanel, MD | Contact | +972533360451 | nataneld@bgu.ac.il | |
| Michael Dubilet, MD | Contact | michaeldu@clalit.org.il |
| Name | Affiliation | Role |
|---|---|---|
| Michael Dubilet, MD | Soroka University Medical Center | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| SorokaUMC | Recruiting | Beersheba | Israel |
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| ID | Term |
|---|---|
| D010149 | Pain, Postoperative |
| ID | Term |
|---|---|
| D011183 | Postoperative Complications |
| D010335 | Pathologic Processes |
| D013568 | Pathological Conditions, Signs and Symptoms |
| D010146 | Pain |
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| 6 months |
| D009461 | Neurologic Manifestations |
| D012816 | Signs and Symptoms |