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There is still no effective antiviral drugs and vaccines against SARS-CoV-2 yet now. This is an obsevational study, the investigators collected the clinical information and clinical outcomes of the COVID-19 patients using anti-2019-nCoV inactivated convalescent plasma.The study is to evaluate the efficacy and safety of anti-2019-nCoV inactivated convalescent plasma in the treatment of COVID-19 pneumonia.
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| Measure | Description | Time Frame |
|---|---|---|
| The virological clearance rate of throat swabs, sputum, or lower respiratory tract secretions at day 1 | The SARS-CoV-2 nuclei acid was quantified using RT-PCR | 1 day after receiving plasma transmission |
| The virological clearance rate of throat swabs, sputum, or lower respiratory tract secretions at day 3 | 3 days after receiving plasma transmission | |
| The virological clearance rate of throat swabs, sputum, or lower respiratory tract secretions at day 7 | 7 days after receiving plasma transmission | |
| Numbers of participants with different Clinical outcomes | Clinical outcomes include death, critical illness, recovery | From receiving plasma transmission to 4 weeks |
| Measure | Description | Time Frame |
|---|---|---|
| Number of participants with treatment-related adverse events as assessed by CTCAE v5.0 | 4 weeks after receiving plasma transmission |
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Inclusion Criteria:
Exclusion Criteria:
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Participants received anti-SARS-CoV-2 inactivated convalescent plasma
| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Hongzhou Lu, Ph.D | Contact | +86-021-37990333 | 3222 | luhongzhou@fudan.edu.cn |
| Name | Affiliation | Role |
|---|---|---|
| Hongzhou Lu, Ph.D | Shanghai Public Health Clinical Center | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Shanghai Public Health Clinical Center | Recruiting | Shanghai | Shanghai Municipality | 201508 | China |
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| ID | Term |
|---|---|
| D018352 | Coronavirus Infections |
| ID | Term |
|---|---|
| D003333 | Coronaviridae Infections |
| D030341 | Nidovirales Infections |
| D012327 | RNA Virus Infections |
| D014777 | Virus Diseases |
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| D007239 |
| Infections |