When a meal is eaten, nutrients activate the release of hormones from the bowel into the blood stream. Normally there is a large amount of hormone released, which tells the brain that an individual is full and to stop eating. When people gain weight and become overweight or obese, these hormone signals are reduced, resulting in these people eating more and gaining more weight. This study is investigating mechanisms which may break this cycle by using particular nutrients to restore reduced hormone levels.

Inclusion Criteria:

• Obese but otherwise healthy volunteers,
• body mass index (BMI) of 30-40 kg/m2
• agreement to consume scheduled meals
• ability to understand the study information sheet and instructions in English and able to provide informed consent.

Exclusion Criteria:

• Not meeting any of the exclusion criteria above.
• Major gut surgery
• Major health problems
• Taking medication for diabetes