Frequency Effect of STN-DBS Through the Dual System on FOG in PD

Frequency Effect of Subthalamic Nucleus Deep Brain Stimulation Through the Dual System on Freezing of Gait in Parkinson Disease

We aim to confirm the effect for FOG by changing the frequency through the dual-system approach in PD patients after STN-DBS.

The investigators set two values of frequency (130, 60Hz) in IPG and allow the patients to change the frequencies freely using the patient controller. After four weeks, the investigators will check the UPDRS part I, II, IV, FOG-Q, and PDQ-39 values at each frequency, including the proportion of use of two frequencies.

Inclusion Criteria:

• patients with PD who are aged 30 years or older
• patients with bilateral STN-DBS
• patients who have a FOG at their med "off" state in outpatient clinic or hospitalization, or UPDRS part II FOG subscore above 1

Exclusion Criteria:

• patients without FOG
• patients who have undergone DBS
• patients who have had previous brain surgery
• patients who have undergone reoperation of DBS
• patients who underwent unilateral DBS
• patients with cognitive impairment (MMSE <18)