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Development, implementation and evaluation of the effectiveness of lifestyle recommendations for the prevention of type 2 diabetes in rural population of Ukraine
An oral glucose tolerance test and anthropometric measurements were performed for 300 randomly selected rural residents of the Kyiv region of Ukraine. Persons from impaired glucose regulation category (impaired fasting glucose - IFG) was enrolled to diabetes prevention intervention study (T2DPUA).
Individuals in the IFG category received advice on limiting sugar intake (not more than 25 g per day), increasing physical activity (30 minutes daily). 30 persons from this category were additionally advised to consume insoluble dietary fiber 15 g per day (Vitacel wheat fiber) for 3 months, after which a repeat anthropometric and biochemical study. Objective control of physical activity and body composition is also provided.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Diet | Experimental |
| |
| Physical activity | Experimental |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Physical activity | Other | Moderate activity 150 min per week |
| |
| Measure | Description | Time Frame |
|---|---|---|
| New type 2 diabetes cases | fasting blood glucose level >=6.1 mmol/l | 3 month |
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Inclusion Criteria:
Persons with fasting blood glucose level >=6.1 mmol/l; persons aged 18-79 who signed an informed consent for the study.
Exclusion Criteria:
Known diabetes; acute infectious diseases; other serious diseases
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| Name | Affiliation | Role |
|---|---|---|
| Victor Kravchenko, PhD, Prof | V.P.Komisarenko Institute of Endocrinology and Metabolism | Study Director |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| V.P.Komisarenko Institute of Endocrinology and Metabolism | Kyiv | 04114 | Ukraine |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 41891171 | Derived | Khalangot M, Krasnienkov D, Gurianov V, Zakharchenko T, Barsukov O, Midlovets K, Kravchenko V, Tronko M. Metabolic and Antioxidant Status, Telomere Lengths of Individuals With Prediabetes in Context of 3 Months of Insoluble Dietary Fibre Intake During the SARS-CoV2 Pandemic. Endocrinol Diabetes Metab. 2026 May;9(3):e70210. doi: 10.1002/edm2.70210. |
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| ID | Term |
|---|---|
| D018149 | Glucose Intolerance |
| D003924 | Diabetes Mellitus, Type 2 |
| ID | Term |
|---|---|
| D006943 | Hyperglycemia |
| D044882 | Glucose Metabolism Disorders |
| D008659 | Metabolic Diseases |
| D009750 | Nutritional and Metabolic Diseases |
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| ID | Term |
|---|---|
| D015444 | Exercise |
| ID | Term |
|---|---|
| D009043 | Motor Activity |
| D009068 | Movement |
| D009142 | Musculoskeletal Physiological Phenomena |
| D055687 | Musculoskeletal and Neural Physiological Phenomena |
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30 persons from this category were additionally advised to consume insoluble dietary fiber 15 g per day (Vitacel wheat fiber) for 3 months, after which a repeat anthropometric and biochemical study.
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| Macronutrient modification |
| Other |
Insoluble dietary fiber 15 g per day (Vitacel wheat fiber); sugar limitation |
|
| D003920 | Diabetes Mellitus |
| D004700 | Endocrine System Diseases |