CAR T-CELL Therapy Educational Video Trial

A Randomized Controlled Trial of an Educational Video Tool for Patients Receiving CAR T-Cell Therapy

The purpose of this study is to test a new educational video to help patients and doctors talk about CAR-T cell therapy, a treatment being used in cancer.

- Educational video tool for patients receiving CAR-T cell therapy.

This research study is a Feasibility Study, which is the first-time investigators are examining this educational video tool for patients receiving CAR-T cell therapy.

The research study procedures include screening for eligibility, randomization and a series of questionnaires

Participants will be randomized to one of 2 groups:

• Group A: Educational video tool
• Group B: Standard care

Participants will be in the research study for a month after consent

It is expected that about 80 participants will take part in this research study.

Inclusion Criteria:

• 18 years or age or older
• Established diagnosis of a hematologic malignancy
• Under consideration for CAR T-cell therapy at Massachusetts General Hospital

Exclusion Criteria:

• Significant uncontrolled psychiatric disorders (psychotic disorder, bipolar disorder, major depression) or other co-morbid disease (dementia, cognitive impairment), which the primary oncologist believes prohibits informed consent or participation in the study
• Undergoing CAR T-cell therapy for solid tumor malignancy
• Inability to comprehend English, as the video is currently only available in English at this time