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The aim of this study is to compare the effects of total intravenous anesthesia and inhalation anesthesia methods on postoperative cognitive dysfunction according to Mini Mental State Examination scores and Neuron Specific Enolase levels in lumbar disc herniectomy operations.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| TOTAL INTRAVENOUS ANESTHESIA |
| ||
| INHALATION ANESTHESIA |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| POSTOPERATIVE COGNITIVE DYSFUNCTION | Behavioral | NEURON SPECIFIC ENOLASE LEVELS IN LUMBAR DISC HERNIECTOMY WITH GENERAL ANESTHESIA MODALITIES |
|
| Measure | Description | Time Frame |
|---|---|---|
| MINI MENTAL STATE EXAMINATION TEST | BELOW 27 SCORE IS ASSOSIATED WITH POSTOPERATIVE COGNITIVE DYSFUNCTION | 1 MONTH |
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Inclusion Criteria:
-Lumbal disc herniectomy operation 18-65 age
Exclusion Criteria:
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Lumbal disc herniectomy operation is planned for ASA I, II and III risk group between the ages of 18-65.
| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| UFUK KUYRUKLUYILDIZ | Contact | 05325840554 | drufuk2001@gmail.com |
| Name | Affiliation | Role |
|---|---|---|
| TÜLAY CEREN ÖLMEZTÜRK KARAKURT | ERZINCAN BYU | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Erzincan Byu | Recruiting | Erzincan | Turkey (Türkiye) |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 25838586 | Result | Goswami U, Babbar S, Tiwari S. Comparative evaluation of the effects of propofol and sevoflurane on cognitive function and memory in patients undergoing laparoscopic cholecystectomy: A randomised prospective study. Indian J Anaesth. 2015 Mar;59(3):150-5. doi: 10.4103/0019-5049.153036. | |
| 31306716 | Result | Luescher T, Mueller J, Isenschmid C, Kalt J, Rasiah R, Tondorf T, Gamp M, Becker C, Sutter R, Tisljar K, Schuetz P, Marsch S, Hunziker S. Neuron-specific enolase (NSE) improves clinical risk scores for prediction of neurological outcome and death in cardiac arrest patients: Results from a prospective trial. Resuscitation. 2019 Sep;142:50-60. doi: 10.1016/j.resuscitation.2019.07.003. Epub 2019 Jul 12. |
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| ID | Term |
|---|---|
| D000079690 | Postoperative Cognitive Complications |
| ID | Term |
|---|---|
| D011183 | Postoperative Complications |
| D010335 | Pathologic Processes |
| D013568 | Pathological Conditions, Signs and Symptoms |
| D060825 | Cognitive Dysfunction |
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BLOOD SAMPLES
| Result | Baysalman HB, Oğuz G, Açıkgöz G, Aksakal FN, Ünver SJJotTA, Dergisi ICS-JTAvR. Total İntravenöz ve Desfluran Anestezilerinin Erken Derlenme ve Kognitif Fonksiyonlara Etkileri. 2011;39(1). |
| D003072 | Cognition Disorders |
| D019965 | Neurocognitive Disorders |
| D001523 | Mental Disorders |