Intralesional Vitamin D Injection for Treatment of Common Warts

Efficacy of Intralesional Vitamin D Injection for Treatment of Common Warts: A Randomized Controlled Trial

Researchers are trying to find out if injecting Vitamin D into a wart is an effective treatment.

Inclusion Criteria:

• Adult patients seen at the Mayo Clinic Rochester practices
• Patients suffering from one or more cutaneous warts as diagnosed by the examining physician at baseline visit on typical diagnostic characteristics
• Able to provide consent
• Both recalcitrant and non-recalcitrant warts will be included

Exclusion Criteria:

• Patients with prior use of home or office-based destructive treatments for this wart(s) in the last 1 month with salicylic acid (SA) or cryotherapy
• Immunoadjuvant therapy for warts in the last 4 months (e.g Candida)
• History of vitamin D injection of warts ever
• High-dose vitamin D supplementation (>4,000 IU daily or equivalent) in the preceding 3 months
• Pregnancy or lactation
• Facial or genital warts
• Lesions not felt by the examining clinician to be a wart (e.g., corns or calluses)
• Immunosuppression (to include immunosuppressive medications or conditions as judged by the physician evaluating the patient at the baseline visit).
• Allergy to sesame oil