Researchers are trying to find out if injecting Vitamin D into a wart is an effective treatment.

Inclusion Criteria:

• Adult patients seen at the Mayo Clinic Rochester practices
• Patients suffering from one or more cutaneous warts as diagnosed by the examining physician at baseline visit on typical diagnostic characteristics
• Able to provide consent
• Both recalcitrant and non-recalcitrant warts will be included

Exclusion Criteria:

• Patients with prior use of home or office-based destructive treatments for this wart(s) in the last 1 month with salicylic acid (SA) or cryotherapy
• Immunoadjuvant therapy for warts in the last 4 months (e.g Candida)
• History of vitamin D injection of warts ever
• High-dose vitamin D supplementation (>4,000 IU daily or equivalent) in the preceding 3 months
• Pregnancy or lactation
• Facial or genital warts
• Lesions not felt by the examining clinician to be a wart (e.g., corns or calluses)
• Immunosuppression (to include immunosuppressive medications or conditions as judged by the physician evaluating the patient at the baseline visit).
• Allergy to sesame oil

Adverse events were collected for each subject from the time of first injection of the investigational product until 112 days following the last administration of the investigational product, for a total of approximately 6 months.