Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
LLR was applied for tumors located at the lower edge and lateral segments of the liver that could be resected more easily than posterosuperior segments. With the development of technology and the growing experience of hepatobiliary surgeons, LLR has been expanded to major liver resections, anatomical resections, and donor hepatectomies by skilled surgeons. However, postoperative mortality, mobility and recovery of liver function are associated with major blood loss which is always the main cause of conversion to laparotomy and remains a challenge for surgeons. Pringle first described the method to arrest the hepatic hemorrhage by compression of the porta hepatis and this procedure was widely spread as well as in laparoscopic feild currently. Here, we described a new modified of Pringle maneuver using Bulldog to block vascular during LLR, and compared its effects with traditional pringle maneuver.
With the innovations of laparoscopic technique and specialized equipment , laparoscopic liver resection became the dominating resection surgery approach. December of 2014, laparoscopic hepatectomy was carried out in our department, extracorporeal Pringle maneuver has been applied in most laparoscopic liver resections which need to block the hepatic inflow, cotton tape was the frequently used tourniquet. We used to blocked the hepatic inflow by extracorporeal Pringle maneuver method with cotton tape for its validity , softness and no visible damages for vessel, but it was always difficult for clamping in a two-dimensional view to encircle the hepatoduodenal ligament , and it delayed operation time for freshmen. Bulldog has been widely used in urinary surgery for vascular occlusion, but bulldog in hepatic surgery has rarely been mentioned, this is the first report to formally demonstrate the clinical application in hepatic surgery. However, it is not clear that whether the bulldog for vascular occlusion is useful and easy to implement in laparoscopic hepatectomy. In this study, we will compare the cotton and the bulldog for vascular occlusion during laparoscopic hepatectomy
Not provided
Not provided
Not provided
Not provided
| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Bulldog tourniquet in laparoscopic Hepatectomy | Experimental | The bulldog tourniquet , a reusable vessel occlusion instrument forblocking the liver inflow-blood in laparoscopic liver resection, was uniformly employed in all patients randomized to Bulldog laparoscopic hepatectom group in the present study. |
|
| cotton tourniquet in laparoscopic Hepatectomy | Active Comparator | The cotton tourniquet ,a reusable vessel occlusion instrument for blocking the liver inflow-blood in laparoscopic liver resection |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| BULLDOG ,A Useful Vascular Occlusion Tourniquet In Laparoscopic Liver Resection | Procedure | Bulldog is an effectively performed approach for vascular occlusion during laparoscopic hepatectomy than traditional Pringle manuever. |
| Measure | Description | Time Frame |
|---|---|---|
| Blood loss | the volume of blood loss | intraoperative |
| Measure | Description | Time Frame |
|---|---|---|
| Liver functional recovery | AST(glutamic oxalacetic transaminase, u/l) | up to 7 days after liver resection |
| Postoperative complication(Rates in different grades) | According to The Clavien-Dindo Classification,https://www.assessurgery.com/clavien-dindo-classification/ |
Not provided
Inclusion Criteria:
Exclusion Criteria:
Not provided
Not provided
Not provided
Not provided
| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Liang He, Master | Contact | 13655600231 | +86 | heliang20062007@163.com |
Not provided
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| The 2nd affiliated hospital of Anhui Medical University | Hefei | Anhui | 230601 | China |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 18035269 | Background | Maehara S, Adachi E, Shimada M, Taketomi A, Shirabe K, Tanaka S, Maeda T, Ikeda K, Higashi H, Maehara Y. Clinical usefulness of biliary scope for Pringle's maneuver in laparoscopic hepatectomy. J Am Coll Surg. 2007 Dec;205(6):816-8. doi: 10.1016/j.jamcollsurg.2007.06.297. Epub 2007 Sep 18. No abstract available. | |
| 25159645 | Background |
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
| cotton tourniquet | Procedure | cotton tourniquet |
|
| up to 30 days after liver resection |
| Mortality rates | the rate of postoperative death | up to 30 days after liver resection |
| Hospital duration after operation (days) | the length of hospital stay | up to 30 days after liver resection |
| Operation time(min) | the during of operation | intraoperative |
| Blood transfusion (times and units) | intraoperative blood transfusion | intraoperative |
| the clamping and declamping time(s) | the clamping and declamping time of using bulldog or cotton | intraoperative |
| Duration of abdominal drain (days) | Duration of abdominal drain | up to 14 days after liver resection |
| Duration to first flatus (days) | Duration to first flatus | up to 14 days after liver resection |
| Comfort questionnaire measures (GCQ) measures by Kolcaba | GCQ measures by Kolcaba, download from http://www.thecomfortline.com/resources/cq.html | up to 30 days after liver resection |
| Intensive care unit stay(days) | Intensive care unit stay in days | up to 7 days after liver resection |
| Liver functional recovery | ALT(glutamic-pyruvic transaminase enzyme,u/l) | up to 7 days after liver resection |
| Liver functional recovery | TB(total bilirubin,μmol/L) | up to 7 days after liver resection |
| Liver functional recovery | ALB(albumin,g/L) | up to 7 days after liver resection |
| Liver functional recovery | TP(total protein,g/L) | up to 7 days after liver resection |
| Dua MM, Worhunsky DJ, Hwa K, Poultsides GA, Norton JA, Visser BC. Extracorporeal Pringle for laparoscopic liver resection. Surg Endosc. 2015 Jun;29(6):1348-55. doi: 10.1007/s00464-014-3801-6. Epub 2014 Aug 27. |
| 26700223 | Background | Ciria R, Cherqui D, Geller DA, Briceno J, Wakabayashi G. Comparative Short-term Benefits of Laparoscopic Liver Resection: 9000 Cases and Climbing. Ann Surg. 2016 Apr;263(4):761-77. doi: 10.1097/SLA.0000000000001413. |
| 22183106 | Background | Rotellar F, Pardo F, Bueno A, Marti-Cruchaga P, Zozaya G. Extracorporeal tourniquet method for intermittent hepatic pedicle clamping during laparoscopic liver surgery: an easy, cheap, and effective technique. Langenbecks Arch Surg. 2012 Mar;397(3):481-5. doi: 10.1007/s00423-011-0887-3. Epub 2011 Dec 20. |
| 23895579 | Background | Le B, Matulewicz RS, Eaton S, Perry K, Nadler RB. Comparative analysis of vascular bulldog clamps used in robot-assisted partial nephrectomy. J Endourol. 2013 Nov;27(11):1349-53. doi: 10.1089/end.2013.0367. Epub 2013 Oct 18. |
| 28121916 | Background | Kim WJ, Kim KH, Shin MH, Yoon YI, Lee SG. Totally laparoscopic anatomical liver resection for centrally located tumors: A single center experience. Medicine (Baltimore). 2017 Jan;96(4):e5560. doi: 10.1097/MD.0000000000005560. |
| 24622763 | Result | Ikeda T, Toshima T, Harimoto N, Yamashita Y, Ikegami T, Yoshizumi T, Soejima Y, Shirabe K, Maehara Y. Laparoscopic liver resection in the semiprone position for tumors in the anterosuperior and posterior segments, using a novel dual-handling technique and bipolar irrigation system. Surg Endosc. 2014 Aug;28(8):2484-92. doi: 10.1007/s00464-014-3469-y. Epub 2014 Mar 13. |