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In breast reduction surgery, delayed wound healing may increase surgical site infections, cutaneous necrosis and may be related to psychological harm.Some risk factors have been identified : smoking, diabetes, overweight. A normal healing involve cellular and biochemical reactions in which iron plays an important role such as cellular respiration, redox reactions and regulation of genes involved in the cell cycle. This trial will study the relationship between iron stores and postoperative wound healing after bilateral breast reduction surgery in patients without preoperative anaemia.The primary outcome of this trial is the comparison of wound healing at post operative day 15, between patients with and without iron deficiency.
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| Measure | Description | Time Frame |
|---|---|---|
| Proportion of good breast tissue healing on each breast | Good healing is defined as a score of 0, 1 or 2 on a 16 points-specifc scale. The scale evaluate proportion of disunity for periareolar vertical and horizontal incisions | 15 days after surgery |
| Measure | Description | Time Frame |
|---|---|---|
| Evaluation of healing on the 16 points specific scale | 15 days after surgery | |
| Proportion of early complications | up to 15 days after surgery | |
| Proportion of closed drainage orifices |
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Inclusion Criteria:
Exclusion Criteria:
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Cohort of woman who had a scheduled bilateral breast reduction surgery without anemia
| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Aristide Ntahe | Contact | 0142495191 | aristide.ntahe@aphp.fr |
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Saint Louis hospital | Paris | France |
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| ID | Term |
|---|---|
| D018798 | Anemia, Iron-Deficiency |
| D000072836 | Surgical Wound |
| ID | Term |
|---|---|
| D000747 | Anemia, Hypochromic |
| D000740 | Anemia |
| D006402 | Hematologic Diseases |
| D006425 | Hemic and Lymphatic Diseases |
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| 15 days after surgery |
| Correlation between serum ferritin levels before surgery and score on the healing scale | 15 days after surgery |
| Intra-class correlation coefficient for the healing scale | 15 days after surgery |
| D000090463 |
| Iron Deficiencies |
| D019189 | Iron Metabolism Disorders |
| D008659 | Metabolic Diseases |
| D009750 | Nutritional and Metabolic Diseases |
| D014947 | Wounds and Injuries |