Multicenter Large-scale Validation Study of the Interest of Broadband Spectroscopy Analysis (Femto/Attosecond by Infrared Laser) on Liquid Biopsies in Breast Cancer Screening
Multicenter Large-scale Validation Study of the Interest of Broadband Spectroscopy Analysis (Femto/Attosecond by Infrared Laser) on Liquid Biopsies in Breast Cancer Screening
The purpose of this study is to validate the interest of broadband spectroscopy analysis (femto/attosecond by infrared laser) on liquid biopsies in breast cancer screening.
Each patient will have one or more liquid biopsy during the follow-up according to the cohort and have a mammogram at the same time.
Biopsies will be analysed by broadband spectroscopy in order to compare the results to mammogram result.
Inclusion Criteria:
*For all participants :
Adult woman capable of giving informed consent to research participation
Affiliation to the French social security system
>For Control cohort:
Woman participating in organised screening or benefiting from individual follow-up, eligible as such for a mammogram
>For Patient cohort:
woman with invasive breast cancer T0N1, T1N0-1, T2N0-1 (histologically proven) at inclusion and before any cancer treatment
>For Exploratory cohort:
woman carrying the BRCA1/2 mutation, followed according to standard recommendations or
woman carrying the BRCA1/2 mutation suffering from in situ BC discovered on biopsy and histologically confirmed
Exclusion Criteria:
For all participants :
For Patient cohort
- Patients with Stage III/IV or Bilateral Breast Cancer
For Control cohort:
For Exploratory cohort:
Concomitant breast cancer