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| Name | Class |
|---|---|
| University of Sussex | OTHER |
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To validate a new virtual reality (VR) based visual field test against the gold standard clinical perimetry test (Humphrey Visual field test 24-2).
Perimetry (or visual field testing) is a vision test used to evaluate a patient's peripheral vision. It involves a patient fixating on a central target and pressing a button when they see a spot of light in their peripheral vision. It is an important way of deciding whether Glaucoma is progressing or not. Next generation virtual reality (VR) technologies offer an exciting new way of conducting perimetry in either a clinical or home environment, allowing more affordable and more frequent monitoring of disease progression in glaucoma, and an easier and more comfortable experience for patients. The investigators propose to create a perimetry test using a commercially available head mounted display for VR, and to assess its accuracy in glaucoma patients in relation to standard automated perimetry.
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| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Visual field testing using Oculus Rift and Humphrey Visual Field Perimeter | Device | Glaucoma patients at Queen's University, Belfast, will be invited to undergo both Visual field testing using the Oculus Rift and the gold-standard Humphrey 24-2 (Carl Zeiss Meditec, Dublin, CA) at two visits, and evaluating consistency for detecting visual field impairments. | ||
| Visual Field Testing using HUmphrey 24-3 Perimeter | Device | Glaucoma patients at Queen's University, Belfast, will be invited to undergo both Visual field testing using the Oculus Rift and the gold-standard Humphrey 24-2 (Carl Zeiss Meditec, Dublin, CA) at two visits, and evaluating consistency for detecting visual field impairments. |
| Measure | Description | Time Frame |
|---|---|---|
| mean deviation (MD) | Mean deviation in decibels (dB), this is a standard summary measure generated by all perimetric tests and is considered to represent generalised loss of visual function. | All statisitcal analysis will take place once all data collection has ended, average 1 year.. |
| Pattern Standard Deviation | Pattern standard deviation in decibels (dB), this is a standard summary measure generated by all perimetric tests and is considered to represent localised loss of visual function. | All statisitcal analysis will take place once all data collection has ended, average 1 year.. |
| Measure | Description | Time Frame |
|---|---|---|
| Repeatbility of both devices | Bland and Altman plots and intra-class correlation coefficients will be generated for both tests for visit 1 vs visit 2 data. | All statisitcal analysis will take place once all data collection has ended, average 1 year.. |
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Inclusion Criteria:
- Patients with a clinical diagnosis of glaucoma with repeatable defects on standard automated perimetry.
Exclusion Criteria:
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Professor Azuara-Blanco will identify participants who meet the criteria from his NHS clinics at the Shankill Health and Well-being Centre. He is part of both the direct care team and also a co-investigator on this application. Opportunistic sampling will be used to ensure that different severity levels of visual field deficit will be represented within the sample. Identification of potential participants will involve reviewing their patient records.
| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Ruth Hogg, PhD | Contact | 02890971654 | r.e.hogg@qub.ac.uk | |
| Lucie Dalton, BSc | Contact | l.dalton@qub.ac.uk |
| Name | Affiliation | Role |
|---|---|---|
| Ruth E Hogg, PhD | Queen's University, Belfast | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| NI Clinical Research Facility | Recruiting | Belfast | Northern Ireland | BT9 7AB | United Kingdom |
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| Type | Includes Protocol | Includes SAP | Includes ICF | Document Label | Document Date | Document Uploaded Date | Document File Name |
|---|---|---|---|---|---|---|---|
| Prot_SAP | Yes | Yes | No | Study Protocol and Statistical Analysis Plan | Dec 9, 2016 |
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| Mar 4, 2019 |
| Prot_SAP_000.pdf |
| ID | Term |
|---|---|
| D005901 | Glaucoma |
| ID | Term |
|---|---|
| D009798 | Ocular Hypertension |
| D005128 | Eye Diseases |
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