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Sleep problems are common in adolescence and recognized as an international public health concern given their links to a range of adverse outcomes. Adolescents with attention-deficit/hyperactivity disorder (ADHD) experience more sleep problems than their peers, including delayed sleep onset, shorter sleep duration, poorer sleep quality, more sleep variability, and greater daytime sleepiness. Further, research conducted by the investigator's team has shown that sleep problems are strongly associated with - and causal contributors to - functional impairment in adolescents with ADHD, including increased mood, behavior, and academic problems. However, sleep problems are not currently addressed in any evidence-based treatment for adolescents with ADHD, and no study has evaluated an intervention targeting sleep problems in adolescents with ADHD. This is a notable gap in the field since consensus statements on sleep suggest that treating sleep problems may improve ADHD and associated impairments. Evidence-based cognitive-behavioral sleep interventions, including the Transdiagnostic Sleep and Circadian Intervention for Youth (TranS-C) intervention, are effective for improving sleep and associated impairments (e.g., attention, mood) in adolescents with sleep problems. However, these interventions have never been tested in adolescents with ADHD specifically. This will be the first to evaluate a cognitive-behavioral sleep intervention (TranS-C) in adolescents with ADHD who experience co-occurring sleep problems. This study will recruit 15 adolescents with ADHD and sleep problems to enroll in and complete an open trial of the TranS-C intervention to evaluate its feasibility, acceptability, and preliminary efficacy. Findings will provide key pilot data regarding treatment of sleep problems in adolescents with ADHD.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Sleep Treatment | Experimental | This arm consists of the sleep treatment that will be administered to all participants in the single-arm open trial. |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Transdiagnostic Sleep and Circadian Intervention for Youth (TranS-C) | Behavioral | TranS-C adopts a modular approach to reversing the psychosocial, behavioral, and cognitive processes maintaining sleep problems via 4 "cross-cutting" modules (introduced in the first session and included in every session thereafter), 4 core modules and 7 optional modules. TranS-C typically involves 6-8 individual, weekly 50-minute sessions. |
| Measure | Description | Time Frame |
|---|---|---|
| Change in overall sleep quality: Pittsburgh Sleep Quality Index (PSQI) | Overall sleep quality measured used the adolescent-completed Pittsburgh Sleep Quality Index (PSQI) | Immediately after the intervention |
| Measure | Description | Time Frame |
|---|---|---|
| Change in sleep duration | Sleep duration assessed using daily sleep diary | Immediately after the intervention |
| Change in sleep onset | Sleep onset time assessed using daily sleep diary |
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Inclusion Criteria:
Exclusion Criteria:
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Cincinnati Children's Hospital Medical Center | Cincinnati | Ohio | 45229 | United States |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 34738484 | Derived | Becker SP, Duraccio KM, Sidol CA, Fershtman CEM, Byars KC, Harvey AG. Impact of a Behavioral Sleep Intervention in Adolescents With ADHD: Feasibility, Acceptability, and Preliminary Effectiveness From a Pilot Open Trial. J Atten Disord. 2022 May;26(7):1051-1066. doi: 10.1177/10870547211056965. Epub 2021 Nov 5. |
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| ID | Term |
|---|---|
| D001289 | Attention Deficit Disorder with Hyperactivity |
| ID | Term |
|---|---|
| D019958 | Attention Deficit and Disruptive Behavior Disorders |
| D065886 | Neurodevelopmental Disorders |
| D001523 | Mental Disorders |
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This is a single group open trial.
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|
| Immediately after the intervention |
| Change in sleep disturbance | Overall sleep disturbance measured used the parent-completed Children's Sleep Habits Questionnaire (CSHQ) | Immediately after the intervention |
| Change in objective sleep functioning | Objective sleep functioning assessed using actigraphy | Immediately after the intervention |
| Change in circadian preference | Circadian preference assessed with the adolescent-completed Children's Morningness-Eveningness Preference (CMEP) Scale | Immediately after the intervention |