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| ID | Type | Description | Link |
|---|---|---|---|
| NCI-2019-05846 | Registry Identifier | CTRP (Clinical Trial Reporting Program) | |
| 2019-0282 | Other Identifier | M D Anderson Cancer Center |
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| Name | Class |
|---|---|
| National Cancer Institute (NCI) | NIH |
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This trial studies how well a mind-body intervention works in improving overall quality of life in adolescents and young adults with lymphoma. A meditation based mind-body intervention may help lower distress, depressive symptoms, and anxiety in adolescents and young adults coping with lymphoma.
PRIMARY OBJECTIVE:
I. Examine the feasibility of the mind-body intervention in adolescents and young adults (AYAs) with lymphoma.
SECONDARY OBJECTIVE:
I. Establish the initial intervention efficacy regarding psychological distress and cancer symptoms (tertiary objective) relative to an attention control (AC) group.
EXPLORATORY OBJECTIVE:
I. Explore mediation (e.g., mindfulness, compassion, social connection, inflammatory processes) and moderation (e.g., demographic and medical factors) of the intervention effects.
OUTLINE: Patients are randomized to 1 of 2 groups.
GROUP I: Patients attend meditation group sessions over 75 minutes once weekly for up to 5 weeks.
GROUP II: Patients attend educational group sessions over 75 minutes once weekly for up to 5 weeks.
After completion of study intervention, patients are followed at 6 and 12 weeks.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Group I (meditation) | Experimental | Patients attend meditation group sessions over 75 minutes once weekly for up to 5 weeks. |
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| Group II (educational) | Active Comparator | Patients attend educational group sessions over 75 minutes once weekly for up to 5 weeks. |
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| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Educational Intervention | Other | Attend educational sessions |
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| Measure | Description | Time Frame |
|---|---|---|
| Mind-body intervention in (AYAs) Adolescents and Young Adults with Lymphoma Questionnaire | We will examine preliminary evidence of intervention efficacy. Meaning and Purpose (1-5) Strongly Disagree 1- Disagree 2, Neither agree or disagree 3, Agree 4, Strongly agree 5. Day-to-Day Experiences (1-6) Almost Always-1, Very frequently-2, Somewhat Frequently -3, Somewhat Infrequently-4, Very Infrequently-5, Almost Never 6 | Up to 12 weeks |
| Measure | Description | Time Frame |
|---|---|---|
| Psychological distress and cancer symptoms (tertiary objective) relative to an attention control (AC) group Questionnaire | We will examine preliminary evidence of intervention efficacy. Meaning and Purpose (1-5) Strongly Disagree 1- Disagree 2, Neither agree or disagree 3, Agree 4, Strongly agree 5. Day-to-Day Experiences (1-6) Almost Always-1, Very frequently-2, Somewhat Frequently -3, Somewhat Infrequently-4, Very Infrequently-5, Almost Never 6 |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Affiliation | Role |
|---|---|---|
| Kathrin Milbury | M.D. Anderson Cancer Center | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| M D Anderson Cancer Center | Houston | Texas | 77030 | United States |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 41298073 | Derived | Cho D, Ahmed S, Snyder S, Kroll J, Chen M, Roth M, Milbury K. Group-Based Support Interventions for Adolescents and Young Adults With Lymphoma: A Pilot Randomized Controlled Trial. Psychooncology. 2025 Dec;34(12):e70343. doi: 10.1002/pon.70343. |
| Label | URL |
|---|---|
| University of Texas MD Anderson Cancer Center | View source |
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| ID | Term |
|---|---|
| D008223 | Lymphoma |
| ID | Term |
|---|---|
| D009370 | Neoplasms by Histologic Type |
| D009369 | Neoplasms |
| D008232 | Lymphoproliferative Disorders |
| D008206 | Lymphatic Diseases |
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| ID | Term |
|---|---|
| D018479 | Early Intervention, Educational |
| D004522 | Educational Status |
| D008722 | Methods |
| D019122 | Meditation |
| ID | Term |
|---|---|
| D002662 | Child Health Services |
| D003153 | Community Health Services |
| D006296 | Health Services |
| D005159 | Health Care Facilities Workforce and Services |
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| Meditation Therapy | Other | Attend meditation sessions |
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| Questionnaire Administration | Other | Ancillary studies |
|
| Up to 12 weeks |
| D006425 | Hemic and Lymphatic Diseases |
| D007160 | Immunoproliferative Disorders |
| D007154 | Immune System Diseases |
| D011314 | Preventive Health Services |
| D012959 | Socioeconomic Factors |
| D011154 | Population Characteristics |
| D008919 | Investigative Techniques |
| D026441 | Mind-Body Therapies |
| D000529 | Complementary Therapies |
| D013812 | Therapeutics |
| D026443 | Spiritual Therapies |
| D012064 | Relaxation Therapy |
| D001521 | Behavior Therapy |
| D011613 | Psychotherapy |
| D004191 | Behavioral Disciplines and Activities |